Ergebnisse einschränken

Combined with anti‐Nogo‐A antibody treatment, BDNF did not compensate the extra deleterious motor effect caused by large size cervical cord hemisection in adult macaques

Beaud, Marie‐Laure ; Rouiller, Eric M. ; Bloch, Jocelyne ; Mir, Anis ; Schwab, Martin E. ; Schmidlin, Eric

In: CNS Neuroscience & Therapeutics, 2019, p. cns.13213

In spinal cord injured adult mammals, neutralizing the neurite growth inhibitor Nogo‐A with antibodies promotes axonal regeneration and functional recovery, although axonal regeneration is limited in length. Neurotrophic factors such as BDNF stimulate neurite outgrowth and protect axotomized neurons. Can the effects obtained by neutralizing Nogo‐A, inducing an environment favorable for...

Corticotectal projections from the premotor or primary motor cortex after cortical lesion or parkinsonian symptoms in adult macaque monkeys: a pilot tracing study

Fregosi, Michela ; Contestabile, Alessandro ; Badoud, Simon ; Borgognon, Simon ; Cottet, Jérôme ; Brunet, Jean-François ; Bloch, Jocelyne ; Schwab, Martin E. ; Rouiller, Eric M.

In: Frontiers in Neuroanatomy, 2019, vol. 13, p. -

The corticotectal projections, together with the corticobulbar (corticoreticular) projections, work in parallel with the corticospinal tract (CST) to influence motoneurons in the spinal cord both directly and indirectly via the brainstem descending pathways. The tectospinal tract (TST) originates in the deep layers of the superior colliculus. In the present study, we analyzed the...

Changes of motor corticobulbar projections following different lesion types affecting the central nervous system in adult macaque monkeys

Fregosi, Michela ; Contestabile, Alessandro ; Badoud, Simon ; Borgognon, Simon ; Cottet, Jérôme ; Brunet, Jean-François ; Bloch, Jocelyne ; Schwab, Martin E. ; Rouiller, Eric M.

In: European Journal of Neuroscience, 2018, vol. 48, no. 4, p. 2050–2070

THE EFFECT OF INSPIRED OXYGEN CONCENTRATION ON INTRAPULMONARY RIGHT-TO-LEFT SHUNT DURING POSTOPERATIVE MECHANICAL VENTILATION

WOLFF, G. ; GRÄDEL, E. ; RIST, M. ; SCHWAB, T. ; PAVLETIC, B.

In: BJA: British Journal of Anaesthesia, 1972, vol. 44, no. 4, p. 350-354

An engineered IN-1 Fab fragment with improved affinity for the Nogo-A axonal growth inhibitor permits immunochemical detection and shows enhanced neutralizing activity

Fiedler, M. ; Horn, C. ; Bandtlow, C. ; Schwab, M.E. ; Skerra, A.

In: Protein Engineering, 2002, vol. 15, no. 11, p. 931-941

Differential effects of anti-Nogo-A antibody treatment and treadmill training in rats with incomplete spinal cord injury

Maier, Irin C. ; Ichiyama, Ronaldo M. ; Courtine, Grégoire ; Schnell, Lisa ; Lavrov, Igor ; Edgerton, V. Reggie ; Schwab, Martin E.

In: Brain, 2009, vol. 132, no. 6, p. 1426-1440

Nogo-a regulates neural precursor migration in the embryonic mouse cortex

Mathis, C.

In: Cerebral Cortex, 2010, vol. 20, no. 10, p. 2380-2390

Sequential loss of myelin proteins during Wallerian degeneration in the human spinal cord

Buss, A. ; Pech, K. ; Merkler, D. ; Kakulas, B. A. ; Martin, D. ; Schoenen, J. ; Noth, J. ; Schwab, M. E. ; Brook, G. A.

In: Brain, 2005, vol. 128, no. 2, p. 356-364

Dendritic Plasticity in the Adult Rat Following Middle Cerebral Artery Occlusion and Nogo-A Neutralization

Papadopoulos, Catherine M. ; Tsai, Shih-Yen ; Cheatwood, Joseph L. ; Bollnow, Melanie R. ; Kolb, Bryan E. ; Schwab, Martin E. ; Kartje, Gwendolyn L.

In: Cerebral Cortex, 2006, vol. 16, no. 4, p. 529-536

Influence of anti-Nogo-A antibody treatment on the reorganization of callosal connectivity of the premotor cortical areas following unilateral lesion of primary motor cortex (M1) in adult macaque monkeys

Hamadjida, Adjia ; Wyss, Alexander F. ; Mir, Anis ; Schwab, Martin E. ; Belhaj-Saif, Abderaouf ; Rouiller, Eric M.

In: Experimental Brain Research, 2012, vol. 223, no. 3, p. 321-340

Following unilateral lesion of the primary motor cortex, the reorganization of callosal projections from the intact hemisphere to the ipsilesional premotor cortex (PM) was investigated in 7 adult macaque monkeys, in absence of treatment (control; n = 4) or treated with function blocking antibodies against the neurite growth inhibitory protein Nogo-A (n = 3). After functional recovery, though...