Université de Fribourg

Cardiovascular and metabolic responses to tap water ingestion in young humans: does the water temperature matter?

Girona, M. ; Grasser, Erik Konrad ; Dulloo, Abdul G. ; Montani, Jean-Pierre

In: Acta Physiologica, 2014, vol. 211, no. 2, p. 358–370

Aim: Drinking water induces short-term cardiovascular and metabolic changes. These effects are considered to be triggered by gastric distension and osmotic factors, but little is known about the influence of water temperature.Methods: We determined, in a randomized crossover study, the acute cardiovascular and metabolic responses to 500 mL of tap water at 3 °C (cold), 22 °C (room) and...

Université de Fribourg

Interpretation of clinical data and hypothesis testing with the aid of self-collected data from physiology laboratory courses: a teaching approach for medical students

Grasser, Erik Konrad ; Montani, Jean-Pierre

In: Advances in Physiology Education, 2019, vol. 43, no. 4, p. 557–560

More than 50 million scientific articles were published between 1665 and 2009 (4), with millions more expected every year (6). This incomprehensible number accounts for scientific articles alone and does not encompass various “pseudo-scientific” information and articles that are spread, without any peer review process, by social media and blogs, thereby generating a potential source of...

Université de Fribourg

Dose-dependent heart rate responses to drinking water: a randomized crossover study in young, non-obese males

Grasser, Erik Konrad

In: Clinical Autonomic Research, 2020, p. -

The aim of the study was to explore a potential dose effect of water on heart rate responses and markers of vagal tone modulation.Methods: This was a randomized crossover study involving eight men whose heart rate and heart rate variability parameters were continuously measured following ingestion of different volumes of still mineral water (200, 400, 600, and 800 mL).Results: A significant...

Université de Fribourg

Postprandial hypotension in older adults: Can it be prevented by drinking water before the meal?

Grobéty, Bastien ; Grasser, Erik Konrad ; Yepuri, Gayathri ; Dulloo, Abdul G. ; Montani, Jean-Pierre

In: Clinical Nutrition, 2015, vol. 34, no. 5, p. 885–891

Background & aimsAn important consequence of ageing is a tendency for postprandial blood pressure to decline, which can lead to fainting. As a possible countermeasure, we investigated in healthy older adults the impact of drinking water before a breakfast meal on postprandial cardiovascular and autonomic functions.MethodsAfter a stable cardiovascular baseline recording for at least 20 min,...

Université de Fribourg

Time course of cardiovascular responses induced by mental and orthostatic challenges

Lackner, Helmut Karl ; Goswami, Nandu ; Papousek, Ilona ; Roessler, Andreas ; Grasser, Erik Konrad ; Montani, Jean-Pierre ; Jezova, Daniela ; Hinghofer-Szalkay, Helmut

In: International Journal of Psychophysiology, 2010, vol. 75, no. 1, p. 48-53

Cardiovascular responses to single stressors diminish over time. Interaction of different stressors influencing hemodynamic variables, indicative of stress-induced reactivity and physiological responses are, however, poorly understood. We investigated time course of mental (using mental arithmetic, MA) and orthostatic (using head up tilt, HUT) challenges induced responses in 16 males. Three...

Université de Fribourg

Cardiovascular responses to a glucose drink in young male individuals with overweight/obesity and mild alterations in glucose metabolism, but without impaired glucose tolerance

Monnard, Cathriona R. ; Grasser, Erik Konrad

In: European Journal of Nutrition, 2019, p. -

Little is known about whether mild aberrations in glucose metabolism, which are seen in overweight/obese subjects (OW/OB) without impaired glucose tolerance, affect regulator control elements for blood pressure homeostasis. Methods Hence, we measured in age-matched male subjects with normal weight (n = 16; BMI = 22.4 kg m−2) and OW/OB (n = 11; BMI = 28.6 kg m−2) continuous...

Université de Fribourg

Perspective: cardiovascular responses to sugar-sweetened beverages in humans: a narrative review with potential hemodynamic mechanisms

Monnard, Cathriona R ; Grasser, Erik Konrad

In: Advances in Nutrition, 2018, vol. 9, no. 2, p. 70–77

Cardiovascular diseases are still the primary cause of mortality worldwide, with high blood pressure and type 2 diabetes as major promoters. Over the past 3 decades, almost in parallel with the rise in cardiovascular disease incidence, the consumption of sugar-sweetened beverages (SSBs) has increased. In this context, SSBs are potential contributors to weight gain and increase the risk for...

Université de Fribourg

Water ingestion decreases cardiac workload time-dependent in healthy adults with no effect of gender

Monnard, Cathriona R. ; Grasser, Erik Konrad

In: Scientific Reports, 2017, vol. 7, no. 1, p. 7939

Ingestion of water entails a variety of cardiovascular responses. However, the precise effect remains elusive. We aimed to determine in healthy adults the effect of water on cardiac workload and to investigate potential gender differences. We pooled data from two controlled studies where blood pressure (BP) and heart rate (HR) were continuously recorded before and after the ingestion of...