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Université de Fribourg

Plant hormone transporters: what we know and what we would like to know

Park, Jiyoung ; Lee, Youngsook ; Martinoia, Enrico ; Geisler, Markus

In: BMC Biology, 2017, vol. 15, p. 93

Hormone transporters are crucial for plant hormone action, which is underlined by severe developmental and physiological impacts caused by their loss-of-function mutations. Here, we summarize recent knowledge on the individual roles of plant hormone transporters in local and long-distance transport. Our inventory reveals that many hormones are transported by members of distinct transporter...

Université de Fribourg

Arabidopsis BTB/POZ protein-dependent PENETRATION3 trafficking and disease susceptibility

Mao, Hailiang ; Aryal, Bibek ; Langenecker, Tobias ; Hagmann, Jörg ; Geisler, Markus ; Grebe, Markus

In: Nature Plants, 2017, vol. 3, no. 11, p. 854

The outermost cell layer of plant roots (epidermis) constantly encounters environmental challenges. The epidermal outer plasma membrane domain harbours the PENETRATION3 (PEN3)/ABCG36/PDR8 ATP-binding cassette transporter that confers non-host resistance to several pathogens. Here, we show that the Arabidopsis ENDOPLASMIC RETICULUM-ARRESTED PEN3 (EAP3) BTB/POZ-domain protein specifically...

Université de Fribourg

A critical view on abc transporters and their interacting partners in auxin transport

Geisler, Markus ; Aryal, Bibek ; Di Donato, Martin ; Hao, Pengchao

In: Plant and Cell Physiology, 2017, vol. 58, no. 10, p. 1601–1614

Different subclasses of ATP-binding cassette (ABC) transporters have been implicated in the transport of native variants of the phytohormone auxin. Here, the putative, individual roles of key members belonging to the ABCB, ABCD and ABCG families, respectively, are highlighted and the knowledge of their assumed expression and transport routes is reviewed and compared with their mutant phenotypes....

Consortium of Swiss Academic Libraries

Keeping it all together: auxin-actin crosstalk in plant development

Zhu, Jinsheng ; Geisler, Markus

In: Journal Of Experimental Botany, 2015, vol. 66, no. 16, p. 4983-4998

Université de Fribourg

SHADE AVOIDANCE 4 is required for proper auxin distribution in the hypocotyl

Ge, Yanhua ; Yan, Fenglian ; Zourelidou, Melina ; Wang, Meiling ; Ljung, Karin ; Fastner, Astrid ; Hammes, Ulrich Z. ; Donato, Martin Di ; Geisler, Markus ; Schwechheimer, Claus ; Tao, Yi

In: Plant Physiology, 2017, vol. 173, no. 1, p. 788–800

The phytohormone auxin is involved in virtually every aspect of plant growth and development. Through polar auxin transport, auxin gradients can be established, which then direct plant differentiation and growth. Shade avoidance responses are well- known processes that require polar auxin transport. In this study, we have identified a mutant, shade avoidance 4 (sav4), defective in...

Université de Fribourg

Flavonol-induced changes in PIN2 polarity and auxin transport in the Arabidopsis thaliana rol1-2 mutant require phosphatase activity

Kuhn, Benjamin M. ; Nodzyński, Tomasz ; Errafi, Sanae ; Bucher, Rahel ; Gupta, Shibu ; Aryal, Bibek ; Dobrev, Petre ; Bigler, Laurent ; Geisler, Markus ; Zažímalová, Eva ; Friml, Jiří ; Ringli, Christoph

In: Scientific Reports, 2017, vol. 7, p. 41906

The phytohormone auxin is a major determinant and regulatory component important for plant development. Auxin transport between cells is mediated by a complex system of transporters such as AUX1/LAX, PIN, and ABCB proteins, and their localization and activity is thought to be influenced by phosphatases and kinases. Flavonols have been shown to alter auxin transport activity and changes in...

Université de Fribourg

Plant development regulated by cytokinin sinks

Zürcher, Evelyne ; Liu, Jingchun ; Donato, Martin di ; Geisler, Markus ; Müller, Bruno

In: Science, 2016, vol. 353, no. 6303, p. 1027–1030

Morphogenetic signals control the patterning of multicellular organisms. Cytokinins are mobile signals that are perceived by subsets of plant cells. We found that the responses to cytokinin signaling during Arabidopsis development are constrained by the transporter PURINE PERMEASE 14 (PUP14). In our experiments, the expression of PUP14 was inversely correlated to the cytokinin signaling...

Université de Fribourg

Master and servant: Regulation of auxin transporters by FKBPs and cyclophilins

Geisler, Markus ; Bailly, Aurélien ; Ivanchenko, Maria

In: Plant Science, 2016, vol. 245, p. 1–10

Plant development and architecture are greatly influenced by the polar distribution of the essential hormone auxin. The directional influx and efflux of auxin from plant cells depends primarily on AUX1/LAX, PIN, and ABCB/PGP/MDR families of auxin transport proteins. The functional analysis of these proteins has progressed rapidly within the last decade thanks to the establishment of...