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Université de Fribourg

Dissociated lateralization of transient and sustained blood oxygen level-dependent signal components in human primary auditory cortex

Lehmann, Christoph ; Herdener, Marcus ; Schneider, Peter ; Federspiel, Andrea ; Bach, Dominik R. ; Esposito, Fabrizio ; di Salle, Francesco ; Scheffler, Klaus ; Kretz, Robert ; Dierks, Thomas ; Seifritz, Erich

In: NeuroImage, 2007, vol. 34, no. 4, p. 1637-1642

Among other auditory operations, the analysis of different sound levels received at both ears is fundamental for the localization of a sound source. These so-called interaural level differences, in animals, are coded by excitatory–inhibitory neurons yielding asymmetric hemispheric activity patterns with acoustic stimuli having maximal interaural level differences. In human auditory cortex, the...

Université de Fribourg

Developmental changes in Parvalbumin regulate presynaptic Ca²⁺ signaling

Collin, Thibault ; Chat, Mireille ; Lucas, Marie Gabrielle ; Moreno, Herman ; Racay, Peter ; Schwaller, Beat ; Marty, Alain ; Llano, Isabel

In: The Journal of Neuroscience, 2005, vol. 25, no. 1, p. 96-107

Certain interneurons contain large concentrations of specific Ca²⁺-binding proteins (CBPs), but consequences on presynaptic Ca²⁺ signaling are poorly understood. Here we show that expression of the slow CBP parvalbumin (PV) in cerebellar interneurons is cell specific and developmentally regulated, leading to characteristic changes in presynaptic Ca²⁺ dynamics (Cai). Using...