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    Université de Fribourg

    Cluster-Driven dynamical arrest in concentrated lysozyme solutions

    Cardinaux, Frédéric ; Zaccarelli, Emanuela ; Stradner, Anna ; Bucciarelli, Saskia ; Farago, Bela ; Egelhaaf, Stefan U. ; Sciortino, Francesco ; Schurtenberger, Peter

    In: The Journal of Physical Chemistry B, 2011, vol. 115, no. 22, p. 7227–7237

    We present a detailed experimental and numerical study of the structural and dynamical properties of salt-free lysozyme solutions. In particular, by combining small-angle X-ray scattering (SAXS) data with neutron spin echo (NSE) and rheology experiments, we are able to identify that an arrest transition takes place at intermediate densities, driven by the slowing down of the cluster motion. Using...

    Université de Fribourg

    Equilibrium cluster formation in concentrated protein solutions and colloids

    Stradner, Anna ; Sedgwick, Helen ; Cardinaux, Frédéric ; Poon, Wilson C. K. ; Egelhaaf, Stefan U. ; Schurtenberger, Peter

    In: Nature, 2004, vol. 432, p. 492-495

    Controlling interparticle interactions, aggregation and cluster formation is of central importance in a number of areas, ranging from cluster formation in various disease processes to protein crystallography and the production of photonic crystals. Recent developments in the description of the interaction of colloidal particles with short-range attractive potentials have led to interesting...