Université de Neuchâtel

Investigation of second coordination sphere interactions between biotinylated coordination complexes and (strept)avidin : CD spectroscopy as a powerful tool for stability constant determinations = Etude des interactions de seconde sphère de coordination entre des complexes de coordination biotinylés et la (strept)avidine: la spectroscopie CD comme technique puissante pour la détermination des constantes de stabilité

Loosli, Andreas ; Ward, Thomas (Dir.)

Thèse de doctorat : Université de Neuchâtel, 2004 ; 1787.

A wide variety of physiological processes in nature is the reflection of ligand interactions with macromolecules, especially with proteins. Among such interactions, the most common are those between enzymes and their substrates and with other molecules that influence activity (e.g. coenzymes). The present work focuses on the interaction between proteins and small molecules. Macromolecules (e.g....