Université de Fribourg

Assessment of the potential for in-plume sulphur dioxide gas-ash interactions to influence the respiratory toxicity of volcanic ash

Tomašek, Ines ; Damby, David E. ; Horwell, Claire J. ; Ayris, Paul M. ; Delmelle, Pierre ; Ottley, Christopher J. ; Cubillas, Pablo ; Casas, Ana S. ; Bisig, Christoph ; Petri-Fink, Alke ; Dingwell, Donald B. ; Clift, Martin J. D. ; Drasler, Barbara ; Rothen-Rutishauser, Barbara

In: Environmental Research, 2019, vol. 179, p. 108798

Volcanic plumes are complex environments composed of gases and ash particles, where chemical and physical processes occur at different temperature and compositional regimes. Commonly, soluble sulphate- and chloride-bearing salts are formed on ash as gases interact with ash surfaces. Exposure to respirable volcanic ash following an eruption is potentially a significant health concern. The...

Université de Fribourg

Respiratory hazard assessment of combined exposure to complete gasoline exhaust and respirable volcanic ash in a multicellular human lung model at the air-liquid interface

Tomašeka, Ines ; J.Horwell, Claire ; Bisig, Christoph ; E.Damby, David ; Comte, Pierre ; Czerwinski, Jan ; Petri-Finkb, Alke ; J.D.Clift, Martin ; Drasler, Barbara ; Rothen-Rutishauser, Barbara

In: Environmental Pollution, 2018, vol. 238, p. 977–987

Communities resident in urban areas located near active volcanoes can experience volcanic ash exposures during, and following, an eruption, in addition to sustained exposures to high concentrations of anthropogenic air pollutants (e.g., vehicle exhaust emissions). Inhalation of anthropogenic pollution is known to cause the onset of, or exacerbate, respiratory and cardiovascular diseases. It...

Université de Fribourg

Assessment of lung cell toxicity of various gasoline engine exhausts using a versatile in vitro exposure system

Bisig, Christoph ; Comte, Pierre ; Güdel, Martin ; Czerwinski, Jan ; Mayer, Andreas ; Müller, Loretta ; Petri-Fink, Alke ; Rothen-Rutishauser, Barbara

In: Environmental Pollution, 2018, vol. 235, p. 263–271

Adverse effect studies of gasoline exhaust are scarce, even though gasoline direct injection (GDI) vehicles can emit a high number of particles. The aim of this study was to conduct an in vitro hazard assessment of different GDI exhausts using two different cell culture models mimicking the human airway. In addition to gasoline particle filters (GPF), the effects of two lubrication oils with...

Université de Fribourg

Diesel exhaust: current knowledge of adverse effects and underlying cellular mechanisms

Steiner, Sandro ; Bisig, Christoph ; Petri-Fink, Alke ; Rothen-Rutishauser, Barbara

In: Archives of Toxicology, 2016, p. 1–13

Diesel engine emissions are among the most prevalent anthropogenic pollutants worldwide, and with the growing popularity of diesel-fueled engines in the private transportation sector, they are becoming increasingly widespread in densely populated urban regions. However, a large number of toxicological studies clearly show that diesel engine emissions profoundly affect human health. Thus the...

Université de Fribourg

Biological effects in lung cells In vitro of exhaust aerosols from a gasoline passenger car with and without particle filter

Bisig, Christoph ; Steiner, Sandro ; Comte, Pierre ; Czerwinski, Jan ; Mayer, Andreas ; Petri-Fink, Alke ; Rothen-Rutishauser, Barbara

In: Emission Control Science and Technology, 2015, vol. 1, no. 3, p. 237–246

Exhaust aerosol from gasoline passenger cars is a complex mixture of a particulate fraction as well as volatile compounds. In contrary to the observed adverse effects of diesel exhaust particles the gasoline exhaust has, however, received little attention so far. The aim of this study was to perform a comparison of exhaust composition and biological responses from freshly produced...