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    Université de Fribourg

    Flavonol-induced changes in PIN2 polarity and auxin transport in the Arabidopsis thaliana rol1-2 mutant require phosphatase activity

    Kuhn, Benjamin M. ; Nodzyński, Tomasz ; Errafi, Sanae ; Bucher, Rahel ; Gupta, Shibu ; Aryal, Bibek ; Dobrev, Petre ; Bigler, Laurent ; Geisler, Markus ; Zažímalová, Eva ; Friml, Jiří ; Ringli, Christoph

    In: Scientific Reports, 2017, vol. 7, p. 41906

    The phytohormone auxin is a major determinant and regulatory component important for plant development. Auxin transport between cells is mediated by a complex system of transporters such as AUX1/LAX, PIN, and ABCB proteins, and their localization and activity is thought to be influenced by phosphatases and kinases. Flavonols have been shown to alter auxin transport activity and changes in...

    Université de Fribourg

    7-rhamnosylated flavonols modulate homeostasis of the plant hormone auxin and affect plant development

    Kuhn, Benjamin M. ; Errafi, Sanae ; Bucher, Rahel ; Dobrev, Petre ; Geisler, Markus ; Bigler, Laurent ; Zažímalová, Eva ; Ringli, Christoph

    In: Journal of Biological Chemistry, 2016, vol. 291, no. 10, p. 5385–5395

    Flavonols are a group of secondary metabolites that affect diverse cellular processes. They are considered putative negative regulators of the transport of the phytohormone auxin, by which they influence auxin distribution and concomitantly take part in the control of plant organ development. Flavonols are accumulating in a large number of glycosidic forms. Whether these have distinct...

    Université de Fribourg

    Flavonols accumulate asymmetrically and affect auxin transport in Arabidopsis thaliana

    Kuhn, Benjamin M. ; Geisler, Markus ; Bigler, Laurent ; Ringli, Christoph

    In: Plant Physiology, 2011, p. -

    Flavonoids represent a class of secondary metabolites with diverse functions in plants including UV protection, pathogen defence, and interspecies communication. They are also known as modulators of signalling processes in plant and animal systems and therefore are considered to have beneficial effects as nutraceuticals. The rol1-2 (repressor of lrx1) mutation of Arabidopsis...