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Antimicrobial silver-filled silica nanorattles with low immunotoxicity in dendritic cells

Priebe, Magdalena ; Widmer, Jérôme ; Löwa, Nina Suhartha ; Abram, Sarah-Luise ; Mottas, Inès ; Woischnig, Anne-Kathrin ; Brunetto, Priscilla S. ; Khanna, Nina ; Bourquin, Carole ; Fromm, Katharina M.

In: Nanomedicine: Nanotechnology, Biology and Medicine, 2017, vol. 13, no. 1, p. 11–22

The progression in the use of orthopedic implants has led to an increase in the absolute number of implant infections, triggering a search for more effective antibacterial coatings. Nanorattles have recently gained interest in biomedical applications such as drug delivery, as encapsulation of the cargo inside the hollow structure provides a physical protection from the surrounding...