Université de Fribourg

IncH-type plasmid harboring the blaCTX-M-15, blaDHA-1, and qnrB4 genes recovered from animal isolates

Schlüter, Andreas ; Nordmann, Patrice ; Bonnin, Rémy A. ; Millemann, Yves ; Eikmeyer, Felix G. ; Wibberg, Daniel ; Pühler, Alfred ; Poirel, Laurent

In: Antimicrobial Agents and Chemotherapy, 2014, p. AAC.02695–14

The whole sequence of plasmid pENVA carrying the extended-spectrum ß-lactamase gene blaCTX-M-15 was determined. It has been identified from a series of clonally-related Klebsiella pneumoniae ST274 strains recovered from companion animals. This plasmid was 253,984-bp in-size and harbored, in addition to blaCTX-M-15, a large array of genes encoding...

Université de Fribourg

New Delhi metallo-β-lactamase-producing Acinetobacter baumannii : a novel paradigm for spreading antibiotic resistance genes

Bonnin, Rémy A. ; Poirel, Laurent ; Nordmann, Patrice

In: Future Microbiology, 2013, vol. 9, no. 1, p. 33–41

The impact of carbapenemase production among clinically significant Gram-negative rods is becoming a major medical issue. To date, Acinetobacter baumannii has been considered as a final recipient of carbapenemase genes (imipenemase, Verona metallo-β-lactamase, Guiana extended-spectrum β-lactamase and Klebsiella pneumonia carbapenemase types) from Enterobacteriaceae and ...