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Silver-containing titanium dioxide nanocapsules for combating multidrug-resistant bacteria

Hérault, Nelly ; Wagner, Julia ; Abram, Sarah-Luise ; Widmer, Jérôme ; Horvath, Lenke ; Vanhecke, Dimitri ; Bourquin, Carole ; Fromm, Katharina M

In: International Journal of Nanomedicine, 2020, vol. Volume 15, p. 1267–1281

Background: Joint arthroplasty has improved the quality of life of patients worldwide, but infections of the prosthesis are frequent and cause significant morbidity. Antimicrobial coatings for implants promise to prevent these infections. Methods: We have synthesized nanocapsules of titanium dioxide in amorphous or anatase form containing silver as antibacterial agent and tested their impact ...