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Università della Svizzera italiana

Predicting failures in complex multi-tier systems

Xin, Rui ; Pezzè, Mauro (Dir.)

Thèse de doctorat : Università della Svizzera italiana, 2020 ; 2020INFO017.

Complex multi-tier systems are composed of many distributed machines, feature multi-layer architecture and offer different types of services. Shared complex multi-tier systems, such as cloud systems, reduce costs and improves resource utilization efficiency, with a considerable amount of complexity and dynamics that challenge the reliability of the system. The new challenges of complex...

Università della Svizzera italiana

Less is more : efficient hardware design through Approximate Logic Synthesis

Scarabottolo, Ilaria ; Pozzi, Laura (Dir.)

Thèse de doctorat : Università della Svizzera italiana, 2020 ; 2020INFO023.

As energy efficiency becomes a crucial concern in almost every kind of digital application, Approximate Computing gains popularity as a potential answer to this ever-growing energy quest. Approximate Computing is a design paradigm particularly suited for error- resilient applications, where small losses in accuracy do not represent a significant reduction in the quality of the result. In these...

Université de Fribourg

Neuralink and Beyond: Challenges of Creating an Enhanced Human

Gurtner, Dimitri

(Internal working papers DIUF ; 21-01)

This article is a literature review of Neuralink, brain-machine interfaces (BMIs) and their applications, followed by future possibilities of BMIs and their potential impacts. Currently, BMIs predominantly have therapeutic applications, such as helping people with spinal cord injury by allowing them to control a computer directly with their brain. However, BMIs can also improve learning,...

Università della Svizzera italiana

Retinoic acid sensitivity of triple-negative breast cancer cells characterized by constitutive activation of the NOTCH1 pathway : the role of RARβ

Paroni, Gabriela ; Zanetti, Adriana ; Barzago, Maria Monica ; Kurosaki, Mami ; Guarrera, Luca ; Fratelli, Maddalena ; Troiani, Martina ; Ubezio, Paolo ; Bolis, Marco ; Vallerga, Arianna ; Biancardi, Federica ; Terao, Mineko ; Garattini, Enrico

In: Cancers, 2020, vol. 12, no. 10, p. 23 p

Triple-negative breast cancer (TNBC) is a heterogeneous disease that lacks effective therapeutic options. In this study, we profile eighteen TNBC cell lines for their sensitivity to the anti-proliferative action of all-trans retinoic acid (ATRA). The only three cell lines (HCC-1599, MB- 157 and MDA-MB-157) endowed with ATRA-sensitivity are characterized by genetic aberrations of the NOTCH1-gene,...

Università della Svizzera italiana

Embryological development of the human cranio-facial arterial system : a pictorial review

Bertulli, Lorenzo ; Robert, Thomas

In: Surgical and radiologic anatomy, 2021, p. 13 p

The embryological development of the cerebral vasculature is very complex. Historical and also more recent studies based on human embryos, comparative anatomy and cerebral angiographies allowed us to better understand this vasculature development. The knowledge and understanding of such embryological development are important for physicians interested in neurovascular pathologies. Indeed, all...

Università della Svizzera italiana

Space-time multilevel Monte Carlo methods and their application to cardiac electrophysiology

Ben Bader, Seif ; Benedusi, Pietro ; Quaglino, Alessio ; Zulian, Patrick ; Krause, Rolf

In: Journal of computational physics, 2021, vol. 433, p. 17 p

We present a novel approach aimed at high-performance uncertainty quantification for time-dependent problems governed by partial differential equations. In particular, we consider input uncertainties described by a Karhunen-Loève expansion and compute statistics of high-dimensional quantities-of-interest, such as the cardiac activation potential. Our methodology relies on a close integration...

Università della Svizzera italiana

A transdisciplinary analysis of COVID-19 in Italy : the most affected country in Europe

Ortenzi, Flaminia ; Albanese, Emiliano ; Fadda, Marta

In: International journal of environmental research and public health, 2020, vol. 17, no. 24, p. 12 p

As of 27 March 2020, 199 countries and territories and one international conveyance are affected by the COVID-19 pandemic. As of the same date, Italy represents the third country worldwide in total number of cases and the first one in total number of deaths. The purpose of this study is to analyse the Italian case and identify key problem questions and lessons learned from the Italian...

Haute école de santé Genève

Les facteurs influençant l'auto-prise en charge à domicile des patients lombalgiques chroniques

Dietrich, Solenne ; Dorand, Myriam H. ; Rossier, Jean-Luc (Dir.)

Mémoire de bachelor : Haute école de santé Genève, 2020.

Introduction : La lombalgie chronique non spécifique touche une grande partie de la population mondiale. Le phénomène de chronicité nécessite une approche spécifique, dont une partie d’auto-prise en charge à domicile. Il a été démontré que la pratique d’exercices ou de tout type d’activité physique diminue les symptômes. Ceci est d’autant plus efficace s’il y a adhérence...

Haute école de santé Genève

Les variables cliniques prédictives de la récupération motrice du membre supérieur hémiplégique : un examen de portée

Alder, Virginie ; De Gregorio, Charlotte ; Bruyneel, Anne-Violette (Dir.)

Mémoire de bachelor : Haute école de santé Genève, 2020.

Introduction : La plégie du membre supérieur est l'un des symptômes les plus courants après un accident vasculaire cérébral. L'incertitude quant à sa récupération potentielle est source d'inquiétude et d'incapacité à se projeter pour le patient. Être en mesure de prédire la récupération au moyen de tests que le physiothérapeute est habileté à effectuer aurait plusieurs impacts:...

Haute école de santé Genève

Besoins d’informations nutritionnelles des femmes durant et après un traitement pour un cancer du sein : travail de bachelor

Gonthier, Melissa ; Ansermoz, Aude ; Soguel Alexander, Ludivine (Dir.)

Mémoire de bachelor : Haute école de santé Genève, 2020.

Introduction : Les femmes atteintes du cancer du sein sont à la recherche d’informations dans le but d’éviter des récidives et d’améliorer leur santé. Elles recherchent des comportements sains à adopter suite à leur maladie et disent ne pas trouver les informations qu’il leur faut. Jusqu’à maintenant, ces patientes disent recevoir des informations sur l’atteinte de la...