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Università della Svizzera italiana

From blue to steel-collar jobs : The decline in employment gaps?

Lerch, Benjamin

The adoption of labor-replacing technologies has already displaced thousands of workers in the US. In this paper, I analyze how the adverse effects of the implementation of robots in firms’ production processes are spreading among the population and how they are shaping the composition of labor markets. Exploiting exogenous variation in robot exposure across local labor markets and over time,...

Università della Svizzera italiana

The antibody response to Plasmodium falciparum : cues for vaccine design and the discovery of receptor-based antibodies

Tan, Joshua ; Piccoli, Luca ; Lanzavecchia, Antonio

In: Annual Review of Immunology

P. falciparum remains a serious public health problem and a continuous challenge for the immune system due to the complexity and diversity of the pathogen. Recent advances from several laboratories in the characterization of the antibody response to the parasite have led to the identification of critical targets for protection and revealed a new mechanism of diversification based on the...

Università della Svizzera italiana

Fighting the spread of Covid-19 : was the Swiss lockdown worth it?

Gatti, Nicolò ; Retali, Beatrice

The implementation of a lockdown to control the Covid-19 pandemic has led to a strong debate in several countries. This makes it crucial to shed light on the actual benefits of such kind of policy. To this purpose, we focus on the Swiss lockdown during the first wave of Covid-19 infections and estimate the number of potentially saved lives. To predict the number of deaths in absence of any...

Università della Svizzera italiana

Robots and nonparticipation in the US : where have all the workers gone?

Lerch, Benjamin

This paper analyzes the impact of one of the leading automation technologies of the last decades, industrial robots, on the declining labor force participation in the US. Exploiting exogenous variation in the adoption of robots across local labor markets and over time, I find that, on average, one additional robot drives two workers out of the labor force. Despite the adverse impact of robots,...

Università della Svizzera italiana

Gender-based price discrimination in the annuity market : evidence from Chile

Bello, Piera

This paper studies gender-based price discrimination in the annuity market. The dataset consists of transaction-level data on the universe of individuals accessing the Chilean annuity market in the 2004-2017 period. It exploits the fact that, in Chile, individuals can access the annuity market through three different channels: an independent financial advisor, a sales agent at a company, or...

Università della Svizzera italiana

The environmental cost and the accident externality of driving : evidence from the Swiss franc’s appreciation

Bello, Piera

This study investigates the effects of driving on air quality and road safety by exploiting exogenous variation in traffic flows associated with the Swiss franc’s appreciation. During the Swiss franc’s appreciation, the volume of cars crossing the Swiss-Italian border rose considerably– the higher purchasing power of Swiss francs in the Euro area induced more Italian workers to cross the...

Università della Svizzera italiana

FJProf : profiling fork/join applications on the Java virtual machine

Rosales, Eduardo ; Rosà, Andrea ; Binder, Walter

An efficient fork/join application should maximize parallelism while minimizing overheads, and maximize locality while minimizing contention. However, there is no unique optimal implementation that best resolves such tradeoffs and failing in balancing them may lead to fork/join applications suffering from several issues (e.g., suboptimal forking, load imbalance, excessive synchronization),...

Università della Svizzera italiana

Endoplasmic reticulum and lysosomal quality control of four nonsense mutants of iduronate 2-sulfatase linked to Hunter’s syndrome

Marazza, Alessandro ; Galli, Carmela ; Fasana, Elisa ; Sgrignani, Jacopo ; Burda, Patricie ; Enrico M. A. Fassi ; Matthias Baumgartner ; Andrea Cavalli ; Maurizio Molinari

In: DNA and cell biology

Hunter’s syndrome (mucopolysaccharidosis type II) is a rare X-linked lysosomal storage disorder caused by mutations in the iduronate 2-sulfatase (IDS) gene. Motivated by the case of a child affected by this syndrome, we compared the intracellular fate of wild type IDS (IDSWT) and of four nonsense mutations of IDS (IDSL482X, IDSY452X, IDSR443X and IDSW337X) generating progressively shorter ...

Università della Svizzera italiana

Taxes, traffic jam and spillover in the metropolis

Ly, Tidiane

This paper studies local governments' public policies in a metropolitan area plagued by traffic congestion, where both residents and workers consume local public goods. We develop a new spatial sub-metropolitan tax competition model which features a central city surrounded by suburban towns linked by mobile capital and mobile residents who commute to work. We show that Pareto-efficiency is...

Università della Svizzera italiana

The impact of ambient air pollution on hospital admissions

Filippini, Massimo ; Masiero, Giuliano ; Steinbach, Sandro

In: European Journal of Health Economics

Ambient air pollution is the environmental factor with the most significant impact on human health. Several epidemiological studies provide evidence for an association between ambient air pollution and human health. However, the recent economic literature has challenged the identification strategy used in these studies. This paper contributes to the ongoing discussion by investigating the...