Université de Fribourg

Bimetallic salen-based compounds and their potential applications

Finelli, Alba ; Abram, Sarah-Luise ; Hérault, Nelly ; Crochet, Aurélien ; Fromm, Katharina M.

In: Crystal Growth & Design, 2020, vol. 20, no. 8, p. 4945–4958

The new bimetallic coordination compounds [LNiAg(NO3)], [LCuMn(NO3)2], [LCuCu(NO3)2], [LCuZn(NO3)2], and [{LCuBi(NO3)3}(ACN)] have been synthesized from a salen-type ligand L containing two distinct coordination sites to accommodate (different) metal ions M1 and M2. In the solid state, the formation of 1:1 compounds (LCu:M2) is always observed, but interactions between the compounds lead to ...

Université de Fribourg

Silver-containing titanium dioxide nanocapsules for combating multidrug-resistant bacteria

Hérault, Nelly ; Wagner, Julia ; Abram, Sarah-Luise ; Widmer, Jérôme ; Horvath, Lenke ; Vanhecke, Dimitri ; Bourquin, Carole ; Fromm, Katharina M

In: International Journal of Nanomedicine, 2020, vol. Volume 15, p. 1267–1281

Background: Joint arthroplasty has improved the quality of life of patients worldwide, but infections of the prosthesis are frequent and cause significant morbidity. Antimicrobial coatings for implants promise to prevent these infections. Methods: We have synthesized nanocapsules of titanium dioxide in amorphous or anatase form containing silver as antibacterial agent and tested their impact ...

Université de Fribourg

Sequential multiple-target sensor: In3+, Fe2+, and Fe3+ discrimination by an anthracene-based probe

Finelli, Alba ; Chabert, Valentin ; Hérault, Nelly ; Crochet, Aurélien ; Kim, Cheal ; Fromm, Katharina M.

In: Inorganic Chemistry, 2019, vol. 58, no. 20, p. 13796–13806

Indium is a nonphysiological toxic metal widely used in industry. While misunderstood, its toxicity is proposed to be linked to a perturbation of Fe3+ homeostasis through the binding of In3+ ions to essential iron metalloproteins such as transferrins. Therefore, the monitoring of In3+ and Fe3+ in biological environments is of prime interest for both basic research and diagnosis. Here we...

Université de Fribourg

Ag Nanoencapsulation for Antimicrobial Applications

Abram, Sarah-Luise ; Gagnon, Jacinthe ; Priebe, Magdalena ; Hérault, Nelly ; Fromm, Katharina M.

In: CHIMIA International Journal for Chemistry, 2018, vol. 72, no. 4, p. 249–252

Biomaterial-related infections remain a significant challenge in medicine. Antimicrobial materials on the basis of Ag nanoparticles represent a promising solution for this issue. Therefore several Ag-containing nanocontainers and nanorattles have been synthesized and characterized that exhibit remarkable control over the release of Ag+ as antimicrobial active species. Their biological...

Université de Fribourg

Threading salen-type Cu- and Ni-complexes into one-dimensional coordination polymers: solution versus solid state and the size effect of the alkali metal ion

Finelli, Alba ; Hérault, Nelly ; Crochet, Aurélien ; Fromm, and Katharina M.

In: Crystal Growth & Design, 2018, vol. 18, no. 2, p. 1215–1226

Compartmentalization of metal ions is crucial in biology as well as in materials science. For the synthesis of single source precursors, the preorganization of different metal ions is of particular interest for the low-temperature generation of mixed metal oxides. On the basis of a potentially Ω-shaped salen-type ligand providing an N2O2 as well as an O2O2 coordination site, mixed metal...

Université de Fribourg

Influence of the sacrificial polystyrene removal pathway on the TiO₂ nanocapsule structure

Hérault, Nelly ; Fromm, Katharina M.

In: Helvetica Chimica Acta, 2017, vol. 100, no. 6, p. -

This study demonstrates the significant influence of the polystyrene removal pathway on the TiO₂ nanocapsules obtained from PS@TiO₂ core-shell particles. In a first step, the polystyrene spheres were coated with titanium oxide via hydrolysis and condensation of the titanium precursor to form PS@TiO₂ core-shell particles. Then, the creation of the empty cavity to form TiO₂ nanocapsules was...