In: NeuroImage: Clinical, 2020, vol. 26, p. 102193
Introduction: Anhedonia, a core symptom of Major Depressive Disorder (MDD), manifests as a lack or loss of motivation as reflected by decreased reward responsiveness, at both behavioral and neural (i.e., striatum) levels. Exposure to stressful life events is another important risk factor for MDD. However, the mechanisms linking reward-deficit and stress to MDD remain poorly understood. Here,...
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In: Brain and Behavior, 2019, no. 9, p. 1-21
Introduction: Reward and stress are important determinants of motivated behaviors. Striatal regions play a crucial role in both motivation and hedonic processes. So far, little is known on how cognitive effort interacts with stress to modulate reward processes. This study examines how cognitive effort (load) interacts with an unpredictable acute stressor (threat-of-shock) to modulate motivational...
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Thèse de doctorat : Université de Fribourg, 2019.
Humans have a propensity to pursue rewards and to avoid punishments. The motivation to seek rewards and the ability to experience and to learn from positive consequences are fundamental functions in the reward processing. They promote survival and well-being. However, these functions can be challenged or impaired by stressful events or contexts. To clarify the determinant factors that might...
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In: Frontiers in Psychiatry, 2019, vol. 10, no. 88, p. 1-15
It is well-documented that university students have an increased risk in developing psychological problems because they face multiple stressors. Cognitive, behavioral, and mindfulness-based stress prevention programs were shown to reduce symptoms of anxiety, depression, and perceived stress in university students. However, little is known of their effect on resource activation. Additionally, most...
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