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Université de Fribourg

Life-history evolution and the genetics of fitness components in drosophila melanogaster

Flatt, Thomas

In: Genetics, 2020, vol. 214, no. 1, p. 3–48

Life-history traits or “fitness components”—such as age and size at maturity, fecundity and fertility, age-specific rates of survival, and life span—are the major phenotypic determinants of Darwinian fitness. Analyzing the evolution and genetics of these phenotypic targets of selection is central to our understanding of adaptation. Due to its simple and rapid life cycle, cosmopolitan...

Université de Fribourg

Evolutionary genomics can improve prediction of species’ responses to climate change

Waldvogel, Ann-Marie ; Feldmeyer, Barbara ; Rolshausen, Gregor ; Exposito-Alonso, Moises ; Rellstab, Christian ; Kofler, Robert ; Mock, Thomas ; Schmid, Karl ; Schmitt, Imke ; Bataillon, Thomas ; Savolainen, Outi ; Bergland, Alan ; Flatt, Thomas ; Guillaume, Frederic ; Pfenninger, Markus

In: Evolution Letters, 2020, vol. 4, no. 1, p. 4–18

Global climate change (GCC) increasingly threatens biodiversity through the loss of species, and the transformation of entire ecosystems. Many species are challenged by the pace of GCC because they might not be able to respond fast enough to changing biotic and abiotic conditions. Species can respond either by shifting their range, or by persisting in their local habitat. If populations...

Université de Fribourg

How flies turn food into progeny

Flatt, Thomas

In: eLife, 2019, vol. 8, p. e51289

Sex-optimal diets have different effects on gene expression in female and male flies.

Université de Fribourg

Aging and Its Demographic Measurement

Bronikowski, Anne M. ; Flatt, Thomas

In: Nature Education Knowledge, 2010, vol. 1, no. 12, p. 1-6

This case study highlights the general issues raised earlier. First, that maximum lifespan is not an easily obtainable metric. Specifically, it is unambiguous in the sense that once the last animal dies, it is most definitely dead. But to estimate the variance in maximum lifespan, many replicate populations would need to be followed for each treatment group (with each replicate providing a single...

Université de Fribourg

Mark-recapture Estimates of Survival in Populations of the Asp Viper, Vipera aspis aspis

Flatt, Thomas ; Dummermuth, Stefan ; Anholt, Bradley R.

In: Journal of Herpetology, 1997, vol. 31, no. 4, p. 558-564

We estimated th eannual survivorship of two populations of the asp viper, Vipera aspis aspis, by recapturing known dult individuals in the field over six and nine years respectively. The snakes at the two study sites in th eJura mountains of northwestern Switzerland were active between mid-March and mid-October. Vispera a. aspis is easily captured by hand, has individually recognizable marks...

Université de Fribourg

Winter weather affects asp viper Vipera aspis population dynamics through susceptible juveniles

Altwegg, Res ; Dummermuth, Stefan ; Anholt, Bradley R. ; Flatt, Thomas

In: Oikos, 2005, vol. 110, no. 1, p. 55-66

Detailed studies on mammals and birds have shown that the effects of climate variation on population dynamics often depend on population composition, because weather affects different subsets of a population differently. It is presently unknown whether this is also true for ectothermic animals such as reptiles. Here we show such an interaction between weather and demography for an ectothermic...

Université de Fribourg

Stabilizing factors interact in promoting host–parasite coexistence

Flatt, Thomas ; Scheuring, István

In: Journal of Theoretical Biology, 2004, vol. 228(2), p. 241

Understanding the mechanisms that promote coexistence among species is a fundamental problem in evolutionary ecology. Such mechanisms include environmental noise, spatial population structure, density dependence, and genetic variation. In natural populations such factors may exert combined effects on coexistence. Thus, to disentangle the contribution of several factors to coexistence, their...

Université de Fribourg

Assessing natural variation in genes affecting Drosophila lifespan

Flatt, Thomas

In: Mechanisms of Ageing and Development, 2004, vol. 125(3), p. 155