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Université de Fribourg

Sitting comfortably versus lying down: Is there really a difference in energy expenditure?

Miles-Chan, Jennifer Lynn ; Sarafian, Delphine ; Montani, Jean-Pierre ; Schutz, Yves ; Dulloo, Abdul G.

In: Clinical Nutrition, 2014, vol. 33, no. 1, p. 175–178

Background and aims: Energy expenditure (EE) during sitting is widely assumed to be higher than that while lying down, but supporting evidence is equivocal. Despite this, resting EE in the sitting position is often used as a proxy for basal metabolic rate. Here we investigate whether EE differs in the comfortable seated position compared to supine (lying) position.Methods: EE and respiratory...

Université de Fribourg

Issues in continuous 24-H core body temperature monitoring in humans using an ingestible capsule telemetric sensor

Monnard, Cathriona R. ; Fares, Elie-Jacques ; Calonne, Julie ; Miles-Chan, Jennifer L. ; Montani, Jean-Pierre ; Durrer, Dominique ; Schutz, Yves ; Dulloo, Abdul G.

In: Frontiers in Endocrinology, 2017, vol. 8, p. -

Background: There is increasing interest in the use of pill-sized ingestible capsule telemetric sensors for assessing core body temperature (Tc) as a potential indicator of variability in metabolic efficiency and thrifty metabolic traits. The aim of this study was to investigate the feasibility and accuracy of measuring Tc using the CorTemp® system.Methods: Tc was measured over an average of 20...

Université de Fribourg

The contribution of Swiss scientists to the assessment of energy metabolism

Montani, Jean-Pierre ; Schutz, Yves ; Dulloo, Abdul G.

In: European Journal of Clinical Nutrition, 2018, vol. 72, no. 5, p. 665–679

Although Switzerland is considered a small country, it has its share in discoveries, inventions and developments for the assessment of energy metabolism. This includes seminal contributions to respiratory and metabolic physiology and to devices for measuring energy expenditure by direct and indirect calorimetry in vivo in humans and small animals (as well as in vitro in organs/tissues), for...

Université de Fribourg

Dieting and weight cycling as risk factors for cardiometabolic diseases: who is really at risk?

Montani, Jean-Pierre ; Schutz, Yves ; Dulloo, Abdul G.

In: Obesity Reviews, 2015, vol. 16, p. 7–18

Despite the poor prognosis of dieting in obesity management, which often results in repeated attempts at weight loss and hence weight cycling, the prevalence of dieting has increased continuously in the past decades in parallel to the steadily increasing prevalence of obesity. However, dieting and weight cycling are not limited to those who are obese or overweight as substantial proportions of...

Université de Fribourg

The case of GWAS of obesity: does body weight control play by the rules?

Müller, Manfred J. ; Geisler, Corinna ; Blundell, John ; Dulloo, Abdul G. ; Schutz, Yves ; Krawczak, Michael ; Bosy-Westphal, Anja ; Enderle, Janna ; Heymsfield, Steven B.

In: International Journal of Obesity, 2018, vol. 42, no. 8, p. 1395–1405

As yet, genome-wide association studies (GWAS) have not added much to our understanding of the mechanisms of body weight control and of the etiology of obesity. This shortcoming is widely attributed to the complexity of the issues. The appeal of this explanation notwithstanding, we surmise that (i) an oversimplification of the phenotype (namely by the use of crude anthropometric traits) and...

Université de Fribourg

Body composition-derived BMI cut-offs for overweight and obesity in ethnic Indian and Creole urban children of Mauritius

Ramuth, Harris ; Hunma, Sadhna ; Ramessur, Vinaysing ; Ramuth, Magalutcheemee ; Monnard, Cathriona ; Montani, Jean-Pierre ; Schutz, Yves ; Joonas, Noorjehan ; Dulloo, Abdul G.

In: British Journal of Nutrition, 2020, vol. 124, no. 5, p. 481–492

It is increasingly recognised that the use of BMI cut-off points for diagnosing obesity (OB) and proxy measures for body fatness in a given population needs to take into account the potential impact of ethnicity on the BMI–fat % relationship in order to avoid adiposity status misclassification. This relationship was studied here in 377 Mauritian schoolchildren (200 boys and 177 girls, aged...

Université de Fribourg

Total energy expenditure assessed by doubly labeled water technique and estimates of physical activity in Mauritian children: analysis by gender and ethnicity

Ramuth, Harris ; Schutz, Yves ; Calonne, Julie ; Joonas, Noorjehan ; Dulloo, Abdul G.

In: European Journal of Clinical Nutrition, 2020, vol. 74, no. 3, p. 445–453

In the tropical island of Mauritius, the rise in obesity has accelerated in the past decades, and could be contributed by low physical activity and increased sedentary behavior. The study objectives were to generate the first dataset of total energy expenditure (TEE), to estimate physical activity in Mauritian children, and to explore differences due to gender and ethnicity.Subjects/methods:...

Université de Fribourg

Energy gap in the aetiology of body weight gain and obesity: a challenging concept with a complex evaluation and pitfalls

Schutz, Yves ; Byrne, N. M. ; Dulloo, Abdul G. ; Hills, A. P.

In: Obesity Facts, 2014, vol. 7, no. 1, p. 15–25

The concept of energy gap(s) is useful for understanding the consequence of a small daily, weekly, or monthly positive energy balance and the inconspicuous shift in weight gain ultimately leading to overweight and obesity. Energy gap is a dynamic concept: an initial positive energy gap incurred via an increase in energy intake (or a decrease in physical activity) is not constant, may fade out...