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Université de Fribourg

Feasibility of functional electrical stimulated cycling in subjects with spinal cord injury: an energetic assessment

Perret, Claudio ; Berry, Helen ; Hunt, Kenneth J. ; Donaldson, Nick ; Kakebeeke, Tanja H.

In: Journal of Rehabilitation Medicine, 2010, vol. 42, no. 9, p. 873-875

Objective: To determine the functional electrical stimulated (FES) cycling volume necessary to reach the recommended weekly exercise caloric expenditure of 1000–2200 kcal in FES-trained subjects with paraplegia.Subjects: Eight (7 males, 1 female) FES-trained subjects with traumatic motor and sensory complete paraplegia (AIS A, lesion level between Th3 and Th9) of at least 3 years duration were...

Université de Fribourg

Repair of the injured spinal cord, a joint approach of basic and clinical research

Buchli, Anita D. ; Rouiller, Eric M. ; Mueller, Roland ; Dietz, Volker ; Schwab, Martin E.

In: Neurodegenerative Diseases, 2007, vol. 4, no. 1, p. 51-56

The myelin protein Nogo-A is a potent inhibitor of neurite outgrowth in the central nervous system, thus contributing to the incapacity of fiber tracts in the adult spinal cord to regenerate after injury. In this review we report on a joint approach of different research groups to develop a therapy applying anti-Nogo-A antibodies to the injured spinal cord. While basic researchers took the...