Université de Fribourg

Dedicated photoreceptor pathways in Drosophila larvae mediate navigation by processing either spatial or temporal cues

Humberg, Tim-Henning ; Bruegger, Pascal ; Afonso, Bruno ; Zlatic, Marta ; Truman, James W. ; Gershow, Marc ; Samuel, Aravinthan ; Sprecher, Simon G.

In: Nature Communications, 2018, vol. 9, no. 1, p. 1260

To integrate changing environmental cues with high spatial and temporal resolution is critical for animals to orient themselves. Drosophila larvae show an effective motor program to navigate away from light sources. How the larval visual circuit processes light stimuli to control navigational decision remains unknown. The larval visual system is composed of two sensory input channels,...

Université de Fribourg

Four individually identified paired dopamine neurons signal reward in larval Drosophila

Rohwedder, Astrid ; Wenz, Nana L. ; Stehle, Bernhard ; Huser, Annina ; Yamagata, Nobuhiro ; Zlatic, Marta ; Truman, James W. ; Tanimoto, Hiromu ; Saumweber, Timo ; Gerber, Bertram ; Thum, Andreas S.

In: Current Biology, 2016, vol. 26, no. 5, p. 661–669

Dopaminergic neurons serve multiple functions, including reinforcement processing during associative learning [1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 and 12]. It is thus warranted to understand which dopaminergic neurons mediate which function. We study larval Drosophila, in which only approximately 120 of a total of 10,000 neurons are dopaminergic, as judged by the expression of tyrosine...