Université de Fribourg

Motor axonal sprouting and neuromuscular junction loss in an animal model of Charcot-Marie-Tooth disease

Ang, Eng-Tat ; Schafer, Ralf ; Baltensperger, Richard ; Wernig, Anton ; Celio, Marco ; Sancho Oliver, Sara

In: Journal of Neuropathology & Experimental Neurology, 2010, vol. 69, no. 3, p. 281-293

Muscle weakness in Charcot-Marie-Tooth Type 1A disease (CMT1A) caused by mutations in peripheral myelin protein 22 (PMP22) has been attributed to an axonopathy that results in denervation and muscle atrophy. The underlying pathophysiological mechanisms involved are not understood. We investigated motor performance, neuromuscular junctions (NMJs), physiological parameters, and muscle morphometry...

Université de Fribourg

Phylogenetic constraints and adaptation explain food-web structure

Cattin, Marie-France ; Bersier, Louis-Félix ; Banašek-Richter, Carolin ; Baltensperger, Richard ; Gabriel, Jean-Pierre

In: Nature, 2004, vol. 427, p. 835-839

Food webs are descriptions of who eats whom in an ecosystem. Although extremely complex and variable, their structure possesses basic regularities. A fascinating question is to find a simple model capturing the underlying processes behind these repeatable patterns. Until now, two models have been devised for the description of trophic interactions within a natural community. Both are essentially...

Université de Fribourg

Radial numerical integrations based on the sinc function

Weber, Valéry ; Daul, Claude A. ; Baltensperger, Richard

In: Computer Physics Communications, 2004, vol. 163(3), p. 133-142

An algorithm for the generation of adaptive radial grids used in density functional theory or quantum chemical calculations is described. Our approach is general and can be applied for the integration over Slater or Gaussian type functions with only minor modifications. The relative error of the integration is fully controlled by the algorithm within a specified range of exponential parameters...

Université de Fribourg

Structural network properties of niche-overlap graphs

Sokhn, Nayla ; Baltensperger, Richard ; Bersier, Louis-Félix ; Nitsche, Ulrich-Ultes ; Hennebert, Jean

In: 2013 International Conference on Signal-Image Technology Internet-Based Systems (SITIS), 2013, p. 478–482

The structure of networks has always been interesting for researchers. Investigating their unique architecture allows to capture insights and to understand the function and evolution of these complex systems. Ecological networks such as food-webs and niche-overlap graphs are considered as complex systems. The main purpose of this work is to compare the topology of 15 real niche-overlap graphs...

Université de Fribourg

Structure comparison of binary and weighted niche-overlap graphs

Sokhn, Nayla ; Baltensperger, Richard ; Bersier, Louis-Félix ; Ultes-Nitsche, Ulrich ; Hennebert, Jean

In: Complex Networks, 2014, vol. 5, p. 119–127

In ecological networks, niche-overlap graphs are considered as complex systems. They represent the competition between two predators that share common resources. The purpose of this paper is to investigate the structural properties of these graphs considered as weighted networks and compare their measures with the ones calculated for the binary networks. To conduct this study, we select four...