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Super resolution imaging of genetically labeled synapses in drosophila brain tissue

Spühler, Isabelle A. ; Conley, Gaurasundar M. ; Scheffold, Frank ; Sprecher, Simon G.

In: Frontiers in Cellular Neuroscience, 2016, p. 142

Understanding synaptic connectivity and plasticity within brain circuits and their relationship to learning and behavior is a fundamental quest in neuroscience. Visualizing the fine details of synapses using optical microscopy remains however a major technical challenge. Super resolution microscopy opens the possibility to reveal molecular features of synapses beyond the diffraction limit....