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How do ethanolamine plasmalogens contribute to order and structure of neurological membranes?

West, Ana ; Zoni, Valeria ; Teague, Walter E. ; Leonard, Alison N. ; Vanni, Stefano ; Gawrisch, Klaus ; Tristram-Nagle, Stephanie ; Sachs, Jonathan N. ; Klauda, Jeffery B.

In: The Journal of Physical Chemistry B, 2020, vol. 124, no. 5, p. 828–839

Ethanolamine plasmalogen (EtnPLA) is a conical-shaped ether lipid and an essential component of neurological membranes. Low stability against oxidation limits its study in experiments. The concentration of EtnPLA in the bilayer varies depending on cell type and disease progression. Here we report on mixed bilayers of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) and 1-(1Z-...