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Identification of PAD2 as a γ-glutamylcysteine synthetase highlights the importance of glutathione in disease resistance of Arabidopsis

Parisy, Vincent ; Poinssot, Benoit ; Owsianowski, Lucas ; Buchala, Antony ; Glazebrook, Jane ; Mauch, Felix

In: The Plant Journal, 2007, vol. 49, no. 1, p. 159-172

The Arabidopsis pad2-1 mutant belongs to a series of non-allelic camalexin-deficient mutants. It was originally described as showing enhanced susceptibility to virulent strains of Pseudomonas syringae and was later shown to be hyper-susceptible to the oomycete pathogen Phytophthora brassicae (formerly P. porri). Surprisingly, in both pathosystems, the disease...