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Università della Svizzera italiana

Short term effects of public smoking bans on health

Mazzonna, Fabrizio ; Salari, Paola

This paper evaluates the causal negative effect of environmental tobacco exposure on health by exploiting the time and geographical variation in public-place smoking bans implemented in Switzerland between 2007 and 2011. Using monthly data from the universe of Swiss hospitals between 2004 and 2012, we show that the incidence of acute myocardial infarction hospitalizations decreases by about...

Università della Svizzera italiana

Unhealthy retirement? Evidence of occupation heterogeneity

Mazzonna, Fabrizio ; Peracchi, Franco

We investigate the causal effect of retirement on health and cognitive abilities by exploiting the variation between and within European countries in old age retirement rules. We show negative and significant effect of retirement on both health and cognitive abilities. We also show evidence of significant heterogeneity across occupational groups. In particular, the negative effect of...

Università della Svizzera italiana

The atypical receptor CCRL2 (C-C Chemokine Receptor-Like 2) does not act as a decoy receptor in endothelial cells

Mazzotti, Chiara ; Gagliostro, Vincenzo ; Bosisio, Daniela ; Del Prete, Annalisa ; Tiberio, Laura ; Thelen, Marcus ; Sozzani, Silvano

In: Frontiers in immunology, 2017, vol. 8, p. 1233

C-C chemokine receptor-like 2 (CCRL2) is a non-signaling seven-transmembrane domain (7-TMD) receptor related to the atypical chemokine receptor (ACKR) family. ACKRs bind chemokines but do not activate G protein-dependent signaling or cell functions. ACKRs were shown to regulate immune functions in vivo by their ability to scavenge chemokines from the local environment. This study was ...

Università della Svizzera italiana

Essays on the demand for child care services

Medici, Diego ; Filippini, Massimo (Dir.)

Thèse de doctorat : Università della Svizzera italiana, 2011 ; 2011ECO009.

In Switzerland, as in many developed countries, a growing number of parents face a pertinent challenge in trying to reconcile family and work commitments. Parents working full-time or part-time may purchase child care services (such as school-meal and after-school services) provided at school or by other professionals, while others directly provide personal care to their children until school...

Università della Svizzera italiana

Benchmarking and regulation in the electricity distribution sector

Mehdi, Farsi ; Fetz, Aurelio ; Filippini, Massimo

In: Servizi pubblici: nuove tendenze nella regolamentazione nella produzione e nel finanziamento, 2007, p. 159-176

In the last two decades electricity distribution sector have witnessed a wave of regulatory reforms aimed at improving efficiency through incentive regulation. Most of these regulation schemes use benchmarking namely measuring a company’s efficiency and rewarding them accordingly. The reliability of efficiency estimates is crucial for an effective implementation of those incentive mechanisms. A...

Consortium of Swiss Academic Libraries

Uncertainty, Information Acquisition, and Price Swings in Asset Markets

Mele, Antonio ; Sangiorgi, Francesco

In: The Review of Economic Studies, 2015, vol. 82, no. 4, p. 1533-1567

Università della Svizzera italiana

Analyzing cultural tourism promotion on Instagram : a cross-cultural perspective

Mele, Emanuele ; Kerkhof, Peter ; Cantoni, Lorenzo

In: Journal of travel & tourism marketing, 2021, vol. 38, no. 3, p. 326-340

A lack of cross-cultural research has been identified regarding cultural tourism promotion on social media. Using the dimensions of Collectivism-Individualism, Power Distance, and High-Context vs. Low-Context communication, we content analyze cultural value differences in Instagram posts promoting cultural tourism – published by the national tourism organizations of Chile, Portugal, USA, and...

Università della Svizzera italiana

Analyzing cultural localization in online tourism promotion

Mele, Emanuele ; Cantoni, Lorenzo (Dir.) ; Kerkhof, Peter (Codir.)

Thèse de doctorat : Università della Svizzera italiana, 2020 ; 2020COM006.

Tourism and culture are strongly intertwined. People can experience culture before, during and after their journey, both in the offline and in the online world. Arguably, the internet is among the main sources of inspiration and information retrieval for tourists, who navigate social media and websites to know more about the destination, its products and services. Following the developments in...

Università della Svizzera italiana

ERK phosphorylation and miR-181a expression modulate activation of human memory TH17 cells

Mele, Federico ; Basso, Camilla ; Leoni, Cristina ; Aschenbrenner, Dominik ; Becattini, Simone ; Latorre, Daniela ; Lanzavecchia, Antonio ; Sallusto, Federica ; Monticelli, Silvia

In: Nature communications, 2015, vol. 6, p. 6431

T helper (TH) cell polarization during priming is modulated by a number of signals, but whether polarization to a given phenotype also influences recall responses of memory TH cells is relatively unknown. Here we show that miR-181a is selectively induced in both human and mouse naive T cells differentiating into the TH17, but not TH1 or TH2 subset. In human memory TH17 cells, miR-181a...