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Université de Fribourg

Relationship Processes in Understudied Samples : Implications for Relationship Functioning and Sexuality in Romantic Relationships

Uhlich, Maximiliane ; Schoebi, Dominik (Dir.)

Thèse de doctorat : Université de Fribourg, 2020.

Relationship functioning can be investigated from different angles; next to investigating dyadic outcomes between couples we can also zoom into processes within subjects. Adopting a cultural lens adds another layer, as the cultural context influences norms around intimate relationships, and can be inspected using the framework of Bronfenbrenner´s (1977) ecological systems theory. In more...

Université de Fribourg

Superconductivity-induced transverse plasma mode and phonon anomaly in the $c$-axis response of the bilayer compound ${\mathrm{RbCa}}_{2}{\mathrm{Fe}}_{4}{\mathrm{As}}_{4}{\mathrm{F}}_{2}$

Xu, Bing ; Munzar, Dominik ; Dubroka, Adam ; Sheveleva, Evgeniia ; Lyzwa, Fryderyk ; Maršík, Premysl ; Wang, C. N. ; Wang, Z. C. ; Cao, G. H. ; Bernhard, Christian

In: Physical Review B, 2020, vol. 101, no. 21, p. 214512

We studied the infrared response of polycrystalline samples of the iron arsenide superconductor (Rb,Cs)Ca2Fe4As4F2 (Rb,Cs-12442), which has a bilayer structure similar to the high-Tc cuprates YBa2Cu3O7 (YBCO) and Bi2Sr2CaCu2O8. The c-axis reflectivity spectra Rc have been derived from the reflectivity spectra of the polycrystalline samples Rpoly and the in-plane spectrum of a corresponding...

Université de Fribourg

Infrared spectroscopy study of the in-plane response of ${\mathrm{YBa}}_{2}{\mathrm{Cu}}_{3}{\mathrm{O}}_{6.6}$ in magnetic fields up to 30 Tesla

Lyzwa, Fryderyk ; Xu, Bing ; Maršík, Premysl ; Sheveleva, Evgeniia ; Crassee, I. ; Orlita, M. ; Bernhard, Christian

In: Physical Review Research, 2020, vol. 2, no. 2, p. 023218

With terahertz and infrared spectroscopy we studied the in-plane response of an underdoped, twinned YBa2Cu3O6.6 single crystal with Tc=58(1)K in high magnetic fields up to B=30 Tesla (T) applied along the c axis. Our goal was to investigate the field-induced suppression of superconductivity and to observe the signatures of the three-dimensional (3D) incommensurate copper charge density wave...

Université de Fribourg

The type I-E CRISPR-Cas system influences the acquisition of bla KPC-IncF plasmid in Klebsiella pneumonia

Zhou, Ying ; Tang, Yu ; Fu, Pan ; Tian, Dongxing ; Yu, Lianhua ; Huang, Yunkun ; Li, Gang ; Li, Meng ; Wang, Yong ; Yang, Zehua ; Xu, Xiaogang ; Yin, Zhe ; Zhou, Dongsheng ; Poirel, Laurent ; Jiang, Xiaofei

In: Emerging Microbes & Infections, 2020, vol. 9, no. 1, p. 1011–1022

Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae (KPC-KP) have disseminated worldwide and emerged as major threats to public health. Of epidemiological significance, the international pandemic of KPC-KP is primarily associated with CG258 isolates and bla KPC-IncF plasmids. CRISPR-Cas system is an adaptive immune system that can hinder gene expansion driven by horizontal gene ...

Université de Fribourg

Does the single-item self-rated health measure the same thing across different wordings? Construct validity study

Cullati, Stéphane ; Bochatay, Naike ; Rossier, Clémentine ; Guessous, Idris ; Burton‑Jeangros, Claudine ; Courvoisier, Delphine S.

In: Quality of Life Research, 2020, p. -

The self-rated health (SRH) item is frequently used in health surveys but variations of its form (wording, response options) may hinder comparisons between versions over time or across surveys. The objectives were to determine (a) whether three SRH forms are equivalent, (b) the form with the best construct validity and (c) the best coding scheme to maximize equivalence across forms.

Université de Fribourg

Study protocol for the ABERRANT study: antibiotic-induced disruption of the maternal and infant microbiome and adverse health outcomes — a prospective cohort study among children born at term

Volery, Maryse ; Scherz, Valentin ; Jakob, William ; Bandeira, Diane ; Deggim-Messmer, Vanessa ; Lauber-Biason, Anna ; Wildhaber, Johannes ; Falquet, Laurent ; Curtis, Nigel ; Zimmermann, Petra

In: BMJ Open, 2020, vol. 10, no. 6, p. e036275

Introduction: There is compositional overlap between the maternal intestinal microbiome, the breast milk microbiome and the infant oral and intestinal microbiome. Antibiotics cause profound changes in the microbiome. However, the effect of intrapartum and early-life antibiotics on the maternal intestinal and breast milk microbiome, and the infant oral and intestinal microbiome, and whether...

Université de Fribourg

Toward specific ways to combine ketamine and psychotherapy in treating depression

Hasler, Gregor

In: CNS Spectrums, 2020, vol. 25, no. 3, p. 445–447

In major depression, remission rate in response to monoaminergic antidepressant is around 50%. The lack of strong synergies between classical antidepressants and psychotherapy may be due to the molecular effects of classical antidepressants. They modulate synapses but they do not substantially influence synaptogenesis. They also increase brain-derived neurotrophic factor (BDNF). However, for...

Université de Fribourg

Increased anxiety after stimulation of the right inferior parietal lobe and the left orbitofrontal cortex

Grieder, Matthias ; Homan, Philipp ; Federspiel, Andrea ; Kiefer, Claus ; Hasler, Gregor

In: Frontiers in Psychiatry, 2020, vol. 11, p. -

Sustained anxiety is a key symptom of anxiety disorders and may be associated with neural activation in the right inferior parietal lobe (rIPL), particularly under unpredictable threat. This finding suggests a moderating role of the rIPL in sustained anxiety, which we tested in the current study. We applied cathodal or sham transcranial direct current stimulation (tDCS) to the rIPL as a...

Université de Fribourg

The role of TNFR2 and DR3 in the in vivo expansion of tregs in T cell depleting transplantation regimens

Rodriguez-Barbosa, Jose-Ignacio ; Schneider, Pascal ; Graca, Luis ; Bühler, Leo ; Perez-Simon, Jose-Antonio ; Rio, Maria-Luisa del

In: International Journal of Molecular Sciences, 2020, vol. 21, no. 9, p. 3347

Regulatory T cells (Tregs) are essential for the maintenance of tolerance to self and non-self through cell-intrinsic and cell-extrinsic mechanisms. Peripheral Tregs survival and clonal expansion largely depend on IL-2 and access to co-stimulatory signals such as CD28. Engagement of tumor necrosis factor receptor (TNFR) superfamily members, in particular TNFR2 and DR3, contribute to promote...

Université de Fribourg

Platelet transforming growth factor-β1 induces liver sinusoidal endothelial cells to secrete interleukin-6

Balaphas, Alexandre ; Meyer, Jeremy ; Perozzo, Remo ; Zeisser-Labouebe, Magali ; Berndt, Sarah ; Turzi, Antoine ; Fontana, Pierre ; Scapozza, Leonardo ; Gonelle-Gispert, Carmen ; Bühler, Leo H.

In: Cells, 2020, vol. 9, no. 5, p. 1311

The roles and interactions of platelets and liver sinusoidal endothelial cells in liver regeneration are unclear, and the trigger that initiates hepatocyte proliferation is unknown. We aimed to identify the key factors released by activated platelets that induce liver sinusoidal endothelial cells to produce interleukin-6 (IL-6), a cytokine implicated in the early phase of liver regeneration....