In: Proceedings of the National Academy of Sciences of the United States of America, 2007, vol. 104, no. 31, p. 12843-12848
Production of TNF-α and IL-1 in infectious and autoimmune diseases is associated with fever, fatigue, and sleep disturbances, which are collectively referred to as sickness behavior syndrome. In mice TNF-α and IL-1 increase nonrapid eye movement sleep. Because clock genes regulate the circadian rhythm and thereby locomotor activity and may alter sleep architecture we assessed the influence of...
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In: Experimental Brain Research, 2005, vol. 162(4), p. 520
Rewards are often not only valued according to their physical characteristics but also relative to other available rewards. The striatum (caudate nucleus, putamen, ventral striatum including nucleus accumbens) is involved in the organization of movement and the processing of reward information. We studied the activity of single striatal neurons in macaques that were presented with different...
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In: Journal of Adolescence, 2018, vol. 68, p. 136-145
Introduction. Prior research has shown that classmates’ behavior serves as a descriptive norm for adolescents’ individual behavior. While earlier studies primarily focused on negative peer influence, classmates’ prosocial behavior might be associated with positive individual development. We hypothesized more classroom- level prosocial behavior predicts a lower likelihood of future...
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In: Evolution, 2004, vol. 58, no. 4, p. 757-767
Learning is thought to be adaptive in variable environments, whereas constant, predictable environments are supposed to favor unconditional, genetically fixed responses. A dichotomous view of behavior as either learned or innate ignores a potential evolutionary interaction between the learned and innate components of a behavioral response. We addressed this interaction in the context of...
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In: Proceedings of the National Academy of Sciences of the United States of America, 2007, vol. 104, no. 32, p. 13051-13055
Knowing which genes contribute to natural variation in learning and memory would help us understand how differences in these cognitive traits evolve among populations and species. We show that a natural polymorphism at the foraging (for) locus, which encodes a cGMP-dependent protein kinase (PKG), affects associative olfactory learning in Drosophila melanogaster. In an assay...
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