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Intracellular sterol transport in eukaryotes, a connection to mitochondrial function ?

Schneiter, Roger

In: Biochimie, 2007, vol. 89, no. 2, p. 255-259

Eukaryotic cells synthesize sterols in the endoplasmatic reticulum (ER) from where it needs to be efficiently transported to the plasma membrane, which harbors not, vert, similar90% of the free sterol pool of the cell. Sterols that are being taken up from the environment, on the other hand, are transported back from the plasma membrane to the ER, where the free sterols are esterified to steryl...