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Université de Fribourg

Differential effects of stimulus characteristics during knee joint perturbation on hamstring and quadriceps reflex responses

Bruhn, Sven ; Leukel, Christian ; Gollhofer, Albert

In: Human Movement Science, 2011, vol. 30, no. 6, p. 1079-1091

When stretching muscles of the ankle joint, stretch velocity and amplitude were shown to selectively influence specific parts of the stretch reflex. The present study investigated whether similar effects can be observed at the knee joint. Seventeen subjects were exposed to sudden anterior tibial translations. The influence of stimulus amplitude was analyzed by applying a low (LIMP) or high...

Université de Fribourg

Cutaneous mechanisms of isometric ankle force control

Choi, Julia T. ; Lundbye-Jensen, Jesper ; Leukel, Christian ; Nielsen, Jens Bo

In: Experimental Brain Research, 2013, p. 1–8

The sense of force is critical in the control of movement and posture. Multiple factors influence our perception of exerted force, including inputs from cutaneous afferents, muscle afferents and central commands. Here, we studied the influence of cutaneous feedback on the control of ankle force output. We used repetitive electrical stimulation of the superficial peroneal (foot dorsum) and medial...

Université de Fribourg

Specific interpretation of augmented feedback changes motor performance and cortical processing

Lauber, Benedikt ; Keller, Martin ; Leukel, Christian ; Gollhofer, Albert ; Taube, Wolfgang

In: Experimental Brain Research, 2013, p. -

It is well established that the presence of external feedback, also termed augmented feedback, can be used to improve performance of a motor task. The present study aimed to elucidate whether differential interpretation of the external feedback signal influences the time to task failure of a sustained submaximal contraction and modulates motor cortical activity. In Experiment 1, subjects had to...

Université de Fribourg

Cross-limb interference during motor learning

Lauber, Benedikt ; Lundbye-Jensen, Jesper ; Keller, Martin ; Gollhofer, Albert ; Taube, Wolfgang ; Leukel, Christian

In: PLoS ONE, 2013, vol. 8, no. 12, p. e81038

It is well known that following skill learning, improvements in motor performance may transfer to the untrained contralateral limb. It is also well known that retention of a newly learned task A can be degraded when learning a competing task B that takes place directly after learning A. Here we investigate if this interference effect can also be observed in the limb contralateral to the trained...

Université de Fribourg

Time to task failure and motor cortical activity depend on the type of feedback in visuomotor tasks

Lauber, Benedikt ; Leukel, Christian ; Gollhofer, Albert ; Taube, Wolfgang

In: PLoS ONE, 2012, vol. 7, no. 3, p. e32433

The present study aimed to elucidate whether the type of feedback influences the performance and the motor cortical activity when executing identical visuomotor tasks. For this purpose, time to task failure was measured during position- and force-controlled muscular contractions. Subjects received either visual feedback about the force produced by pressing a force transducer or about the actual...

Université de Fribourg

Changes in corticospinal transmission following 8 weeks of ankle joint immobilization

Leukel, Christian ; Taube, Wolfgang ; Rittweger, Jörn ; Gollhofer, Albert ; Ducos, Michel ; Weber, Tobias ; Lundbye-Jensen, Jesper

In: Clinical Neurophysiology, 2015, vol. 126, no. 1, p. 131–139

Joint immobilization has previously been shown to modulate corticospinal excitability. The present study investigated changes in the excitability of distinct fractions of the corticospinal pathway by means of conditioning the H-reflex with transcranial magnetic stimulation (TMS) of the primary motor cortex (Hcond). This method allows assessment of transmission in fast (monosynaptic) and slow(er)...

Université de Fribourg

Short-term pressure induced suppression of the short latency response - a new methodology for investigating stretch reflexes

Leukel, Christian ; Lundbye-Jensen, Jesper ; Gruber, Markus ; Zuur, Abraham T. ; Gollhofer, Albert ; Taube, Wolfgang

In: Journal of Applied Physiology, 2009///doi:10.1152/japplphysiol.00301.2009

During experiments involving ischemic nerve block we noticed that the short latency response (SLR) of evoked stretches in m. soleus decreased immediately following inflation of a pneumatic cuff surrounding the lower leg. The present study aimed to investigate this short-term effect of pressure application in more detail. 58 healthy subjects were divided into 7 protocols. Unilateral stretches were...

Université de Fribourg

Subconscious visual cues during movement execution allow correct online choice reactions

Leukel, Christian ; Lundbye-Jensen, Jesper ; Christensen, Mark Schram ; Gollhofer, Albert ; Nielsen, Jens Bo ; Taube, Wolfgang

In: PLoS ONE, 2012, vol. 7, no. 9, p. e44496

Part of the sensory information is processed by our central nervous system without conscious perception. Subconscious processing has been shown to be capable of triggering motor reactions. In the present study, we asked the question whether visual information, which is not consciously perceived, could influence decision-making in a choice reaction task. Ten healthy subjects (28±5 years) executed...

Université de Fribourg

Changes in predictive motor control in drop-jumps based on uncertainties in task execution

Leukel, Christian ; Taube, Wolfgang ; Lorch, Michael ; Gollhofer, Albert

In: Human Movement Science, 2011, p. -

Drop-jumps are controlled by predictive and reactive motor strategies which differ with respect to the utilization of sensory feedback. With reaction, sensory feedback is integrated while performing the task. With prediction, sensory information may be used prior to movement onset. Certainty about upcoming events is important for prediction. The present study aimed at investigating how...

Université de Fribourg

Pathway-specific plasticity in the human spinal cord

Leukel, Christian ; Taube, Wolfgang ; Beck, Sandra ; Schubert, Martin

In: European Journal of Neuroscience, 2012, vol. 35, no. 10, p. 1622-1629

The aim of the present study was to artificially induce plasticity in the human spinal cord and evaluate whether this plasticity is pathway specific. For this purpose, a technique called paired associative stimulation (PAS) was applied. Volleys evoked by transcranial magnetic stimulation over the primary motor cortex and peripheral nerve stimulation of the nervus tibialis in the popliteal...