Université de Fribourg

Dissemination of multiresistant Enterobacter cloacae isolates producing OXA-48 and CTX-M-15 in a Spanish hospital

Fernández, Javier ; Montero, Ignacio ; Martínez, Óscar ; Fleites, Ana ; Poirel, Laurent ; Nordmann, Patrice ; Rodicio, M. Rosario

In: International Journal of Antimicrobial Agents, 2015, vol. 46, no. 4, p. 469–474

Twenty-one multiresistant Enterobacter cloacae isolates producing OXA-48 (n = 10), CTX-M-15 (n = 7) or both (n = 4) β-lactamases were detected in a Spanish hospital during a 1-year period (June 2013 to June 2014). The isolates were also resistant to non-β-lactam antimicrobials, further complicating the therapeutic options. Genotyping of the isolates...

Université de Fribourg

Comparison of three biochemical tests for rapid detection of extended-spectrum β-lactamase-producing Enterobacteriaceae

Poirel, Laurent ; Fernández, Javier ; Nordmann, Patrice

In: Journal of Clinical Microbiology, 2015, p. JCM.01840–15

Enterobacterial isolates producing clavulanic-inhibited extended-spectrum β-lactamases (ESBLs) are increasingly spreading in the community and are often responsible for nosocomial infections. Rapid biochemical tests have been developed recently for their detection. Three tests, namely the Rapid ESBL NDP test, the β-Lacta test and the Rapid ESBL Screen have been evaluated with a collection of...