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Mast cells and macrophages in duodenal mucosa of mice overexpressing erythropoietin

Ribatti, Domenico ; Crivellato, Enrico ; Nico, Beatrice ; Guidolin, Diego ; Gassmann, Max ; Djonov, Valentin

In: Journal of Anatomy, 2009///doi: 10.1111/j.1469-7580.2009.01131.x

There is increasing evidence suggesting a wider biological role of erythropoietin (Epo) and Epo receptor (EpoR) not related to erythropoiesis, such as the detection of EpoR in other cells, i.e. polymorphonuclear leukocytes, megakaryocytes, endothelial, myocardial and neural cells. In this study, by using a mouse model (designated tg6) that constitutively overexpresses human Epo in an...