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Université de Fribourg

The contribution of Swiss scientists to the assessment of energy metabolism

Montani, Jean-Pierre ; Schutz, Yves ; Dulloo, Abdul G.

In: European Journal of Clinical Nutrition, 2018, vol. 72, no. 5, p. 665–679

Although Switzerland is considered a small country, it has its share in discoveries, inventions and developments for the assessment of energy metabolism. This includes seminal contributions to respiratory and metabolic physiology and to devices for measuring energy expenditure by direct and indirect calorimetry in vivo in humans and small animals (as well as in vitro in organs/tissues), for...

Université de Fribourg

Collateral fattening in body composition autoregulation: its determinants and significance for obesity predisposition

Dulloo, Abdul G. ; Miles-Chan, Jennifer L. ; Schutz, Yves

In: European Journal of Clinical Nutrition, 2018, vol. 72, no. 5, p. 657–664

Collateral fattening refers to the process whereby excess fat is deposited as a result of the body’s attempt to counter a deficit in lean mass through overeating. Its demonstration and significance to weight regulation and obesity can be traced to work on energy budget strategies in growing mammals and birds, and to men recovering from experimental starvation. The cardinal features of...

Université de Fribourg

Posture allocation revisited: breaking the sedentary threshold of energy expenditure for obesity management

Miles-Chan, Jennifer L. ; Dulloo, Abdul G.

In: Frontiers in Physiology, 2017, vol. 8, p. -

There is increasing recognition that low-intensity physical activities of daily life play an important role in achieving energy balance and that their societal erosion through substitution with sedentary (mostly sitting) behaviours, whether occupational or for leisure, impact importantly on the obesity epidemic. This has generated considerable interest for better monitoring, characterizing...

Université de Fribourg

Cardiovascular responses to sugary drinks in humans: galactose presents milder cardiac effects than glucose or fructose

Charrière, Nathalie ; Loonam, Cathriona ; Montani, Jean-Pierre ; Dulloo, Abdul G. ; Grasser, Erik K.

In: European Journal of Nutrition, 2017, vol. 56, no. 6, p. 2105–2113

PurposeThere is increasing interest into the potentially beneficial effects of galactose for obesity and type 2 diabetes management as it is a low-glycemic sugar reported to increase satiety and fat mobilization. However, fructose is also a low-glycemic sugar but with greater blood pressure elevation effects than after glucose ingestion. Therefore, we investigated here the extent to which the...

Université de Fribourg

Oral contraceptive pill alters acute dietary protein‐induced thermogenesis in young women

Duhita, Maharani Retna ; Schutz, Yves ; Montani, Jean-Pierre ; Dulloo, Abdul G. ; Miles-Chan, Jennifer L.

In: Obesity, 2017, vol. 25, no. 9, p. 1482–1485

Objective: There is much interest in the role of dietary protein for weight control. However, there remains a need to characterize individual determinants of the thermogenic effects of protein. This study aimed to investigate the influence of menstrual cycle phase and the combined, monophasic oral contraceptive pill on the thermogenic response to a standardized high-protein (HP) versus...

Université de Fribourg

Issues in continuous 24-H core body temperature monitoring in humans using an ingestible capsule telemetric sensor

Monnard, Cathriona R. ; Fares, Elie-Jacques ; Calonne, Julie ; Miles-Chan, Jennifer L. ; Montani, Jean-Pierre ; Durrer, Dominique ; Schutz, Yves ; Dulloo, Abdul G.

In: Frontiers in Endocrinology, 2017, vol. 8, p. -

Background: There is increasing interest in the use of pill-sized ingestible capsule telemetric sensors for assessing core body temperature (Tc) as a potential indicator of variability in metabolic efficiency and thrifty metabolic traits. The aim of this study was to investigate the feasibility and accuracy of measuring Tc using the CorTemp® system.Methods: Tc was measured over an average of 20...