In: Journal of Antimicrobial Chemotherapy, 2015, vol. 70, no. 1, p. 98-102
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In: Journal of Antimicrobial Chemotherapy, 2014, vol. 69, no. 3, p. 623-627
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In: Journal of Antimicrobial Chemotherapy, 2015, vol. 70, no. 11, p. 3014-3022
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In: Diagnostic Microbiology and Infectious Disease, 2015, p. -
The dissemination of carbapenemase-producing bacteria worldwide is an important source of concern because carbapenemase producers are multidrug resistant (Nordmann and Poirel, 2014). National guidelines increasingly recommend a systematic screening of at least carbapenemase-producing Enterobacteriaceae (CPE) and glycopeptide-resistant enterococci (GRE) in patients admitted to hospitals who have...
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In: Journal of Medical Microbiology, 2014, vol. 63, no. Pt_5, p. 772–776
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In: BioMed Research International, 2014, vol. 2014, p. e249856
The emergence of one of the most recently described carbapenemases, namely, the New Delhi metallo-lactamase (NDM-1), constitutes a critical and growingly important medical issue. This resistance trait compromises the efficacy of almost all lactams (except aztreonam), including the last resort carbapenems. Therapeutical options may remain limited mostly to colistin, tigecycline, and fosfomycin....
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In: Antimicrobial Agents and Chemotherapy, 2014, vol. 58, no. 2, p. 1269–1269
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In: Journal of Clinical Microbiology, 2014, p. JCM.00594–14
Multidrug-resistant Acinetobacter baumannii isolates, and particularly carbapenemase-producing isolates, are increasingly reported worldwide. The biochemically-based Carba NP test, extensively validated for detection of carbapenemase producers among Enterobacteriaceae and Pseudomonas spp., has been modified for the detection of carbapenemase production in Acinetobacter spp. A collection of 151...
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In: Antimicrobial Agents and Chemotherapy, 2014, vol. 58, no. 4, p. 2441-2445
A prospective survey was conducted on 862 Enterobacteriaceae with reduced susceptibility to carbapenems. The Carba NP test, UV spectrophotometry and DNA microarray were used for detecting carbapenemase producers, and results compared to PCR and sequencing. The 172 carbapenemase producers were detected using the Carba NP test and UV spectrophotometry whereas DNA microarray failed to detect IMI...
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In: Journal of Antimicrobial Chemotherapy, 2014, vol. 69, no. 3, p. 623-627
Objectives: Carbapenem-resistant Enterobacteriaceae isolates (n = 1485) were received at the French Associated National Reference Center for Antibiotic Resistance in 2012 and were characterized for their mechanism of resistance to carbapenems.Methods: Carbapenemase production was detected using the biochemical-based Carba NP test, based on the detection of in vitro hydrolysis of imipenem. All...
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