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Evaluation of the RAPIDEC® CARBA NP, the Rapid CARB Screen® and the Carba NP test for biochemical detection of carbapenemase-producing Enterobacteriaceae

Dortet, Laurent ; Agathine, Aurélie ; Naas, Thierry ; Cuzon, Gaëlle ; Poirel, Laurent ; Nordmann, Patrice

In: Journal of Antimicrobial Chemotherapy, 2015, vol. 70, no. 11, p. 3014-3022

Multiple colonization with highly resistant bacteria: carbapenemase-producing Enterobacteriaceae, carbapenemase-producing Pseudomonas aeruginosa, carbapenemase-producing Acinetobacter baumannii, and glycopeptide-resistant Enterococcus faecium

Girlich, Delphine ; Nordmann, Patrice ; Lécuyer, Hervé ; Berche, Patrick ; Marmorat-Khuong, Anne ; Gros, Isabelle ; Cuzon, Gaëlle ; Dortet, Laurent

In: Diagnostic Microbiology and Infectious Disease, 2015, p. -

The dissemination of carbapenemase-producing bacteria worldwide is an important source of concern because carbapenemase producers are multidrug resistant (Nordmann and Poirel, 2014). National guidelines increasingly recommend a systematic screening of at least carbapenemase-producing Enterobacteriaceae (CPE) and glycopeptide-resistant enterococci (GRE) in patients admitted to hospitals who have...

Strategy for a rapid detection of carbapenemase-producing Enterobacteriaceae

Dortet, Laurent ; Bréchard, Ludivine ; Cuzon, Gaëlle ; Poirel, Laurent ; Nordmann, Patrice

In: Antimicrobial Agents and Chemotherapy, 2014, vol. 58, no. 4, p. 2441-2445

A prospective survey was conducted on 862 Enterobacteriaceae with reduced susceptibility to carbapenems. The Carba NP test, UV spectrophotometry and DNA microarray were used for detecting carbapenemase producers, and results compared to PCR and sequencing. The 172 carbapenemase producers were detected using the Carba NP test and UV spectrophotometry whereas DNA microarray failed to detect IMI...