Université de Fribourg

Fine-scale spatial patterns of the Tertiary relict Zelkova abelicea (Ulmaceae) indicate possible processes contributing to its persistence to climate changes

Bosque, Marta ; Adamogianni, Maria Irene ; Bariotakis, Michael ; Fazan, Laurence ; Stoffel, Markus ; Garfi, Giuseppe ; Gratzfeld, Joachim ; Kozlowski, Gregor ; Pirintsos, Stergios

In: Regional Environmental Change, 2014, vol. 14, no. 2, p. 835–849

In this paper, the fine-scale spatial patterns of the Tertiary relict Zelkova abelicea (Lam.) Boiss. were studied (1) to reveal processes that contributed to its persistence to climate changes and (2) to assist future conservation planning, with the purpose of shifting the attention of conservation practitioners from patterns to processes. Results of the fine-scale spatial patterns of Z. abelicea...

Université de Fribourg

Plastic modifications within inhibitory control networks induced by practicing a stop-signal task: an electrical neuroimaging study

Manuel, Aurelie L. ; Bernasconi, Fosco ; Spierer, Lucas

In: Cortex, 2012, p. -

Inhibitory control refers to our ability to suppress ongoing motor, affective or cognitive processes and mostly depends on a fronto–basal brain network. Inhibitory control deficits participate in the emergence of several prominent psychiatric conditions, including attention deficit/hyperactivity disorder or addiction. The rehabilitation of these pathologies might therefore benefit from...

Université de Fribourg

The brain-specific Neural Zinc Finger transcription factor 2b (NZF-2b/7ZFMyt1) causes suppression of cocaine-induced locomotor activity

Chandrasekar, Vijay ; Dreyer, Jean-Luc

In: Neurobiology of Disease, 2009, vol. 37, no. 1, p. 86-98

Chronic cocaine induces high expression of the brain-specific Neural-Zinc-Finger transcription factor-2b (NZF-2b/7ZFMyt1), particularly in the mesolimbic dopaminergic pathway, resulting in a 11-fold increase in NZF-2b/7ZFMyt1 expression in the Nucleus Accumbens (NAc). Overexpression of this gene in the NAc with a NZF-2b/7ZFMyt1-expressing lentivirus resulted in >55% decrease in locomotor activity...