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Université de Fribourg

Towards a photochemical synthesis of peptides

Bochet, Christian G.

In: CHIMIA International Journal for Chemistry, 2013, vol. 67, no. 12, p. 896–898

The laboratory preparation of peptides, once a challenge, is now a standard operation that can be automatised. However, the need for particular protecting groups requiring relatively harsh conditions for their removal (strong acids or bases) and reactive coupling agents can be problematic in specific cases (e.g. in a cell or in a microfluidic device). In this account, we describe our efforts...