Université de Neuchâtel

Rhodium(I) iminophosphine poly(propyleneimine) dendrimers: Synthesis, characterization and molecular structure of a mononuclear analogue

Antonels, Nathan C. ; Therrien, Bruno ; Moss, John R. ; Smith, Gregory S.

In: Inorganic Chemistry Communications, 2009, vol. 12, no. 8, p. 716-719

First (G1)- and second-generation (G2) poly(propyleneimine) (PPI) dendrimers were reacted with 2-(diphenylphosphino)benzaldehyde, to form iminophosphine-functionalised dendritic ligands (1, 2). The reaction of the dimeric precursor [RhCl(CO)2]2 with the heterobidentate dendritic ligands 1, 2 gave the corresponding rhodium(I)...

Université de Neuchâtel

Anticancer activity of multinuclear arene ruthenium complexes coordinated to dendritic polypyridyl scaffolds

Govender, Preshendren ; Antonels, Nathan C. ; Mattsson, Johan ; Renfrew, Anna K. ; Dyson, Paul J. ; Moss, John R. ; Therrien, Bruno ; Smith, Gregory S.

In: Journal of Organometallic Chemistry, 2009, vol. 694, no. 21, p. 3470-3476

The rational development of multinuclear arene ruthenium complexes (arene = p-cymene, hexamethylbenzene) from generation 1 (G1) and generation 2 (G2) of 4-iminopyridyl based poly(propyleneimine) dendrimer scaffolds of the type, DAB-(NH2)n (n = 4 or 8, DAB = diaminobutane) has been accomplished in order to exploit the ‘enhanced...