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    Université de Fribourg

    Bimetallic salen-based compounds and their potential applications

    Finelli, Alba ; Abram, Sarah-Luise ; Hérault, Nelly ; Crochet, Aurélien ; Fromm, Katharina M.

    In: Crystal Growth & Design, 2020, vol. 20, no. 8, p. 4945–4958

    The new bimetallic coordination compounds [LNiAg(NO3)], [LCuMn(NO3)2], [LCuCu(NO3)2], [LCuZn(NO3)2], and [{LCuBi(NO3)3}(ACN)] have been synthesized from a salen-type ligand L containing two distinct coordination sites to accommodate (different) metal ions M1 and M2. In the solid state, the formation of 1:1 compounds (LCu:M2) is always observed, but interactions between the compounds lead to ...

    Université de Fribourg

    Silver-containing titanium dioxide nanocapsules for combating multidrug-resistant bacteria

    Hérault, Nelly ; Wagner, Julia ; Abram, Sarah-Luise ; Widmer, Jérôme ; Horvath, Lenke ; Vanhecke, Dimitri ; Bourquin, Carole ; Fromm, Katharina M

    In: International Journal of Nanomedicine, 2020, vol. Volume 15, p. 1267–1281

    Background: Joint arthroplasty has improved the quality of life of patients worldwide, but infections of the prosthesis are frequent and cause significant morbidity. Antimicrobial coatings for implants promise to prevent these infections. Methods: We have synthesized nanocapsules of titanium dioxide in amorphous or anatase form containing silver as antibacterial agent and tested their impact ...

    Université de Fribourg

    Synthesis and applications of nanocontainers and nanorattles

    Abram, Sarah-Luise ; Yep, Philippe ; Fromm, Katharina M.

    In: CHIMIA International Journal for Chemistry, 2019, vol. 73, no. 1, p. 12–16

    Nanorattles and hollow nanocontainers have unique properties related to the presence of a void space inside the shell, which has been shown to improve the properties of materials for e.g. catalysis, drug release, sensor materials or lithium ion batteries. This article summarizes our recent progress in the synthesis of hollow silica, titania and ceria nanorattles and nanocontainers, eventually...

    Université de Fribourg

    Ag Nanoencapsulation for Antimicrobial Applications

    Abram, Sarah-Luise ; Gagnon, Jacinthe ; Priebe, Magdalena ; Hérault, Nelly ; Fromm, Katharina M.

    In: CHIMIA International Journal for Chemistry, 2018, vol. 72, no. 4, p. 249–252

    Biomaterial-related infections remain a significant challenge in medicine. Antimicrobial materials on the basis of Ag nanoparticles represent a promising solution for this issue. Therefore several Ag-containing nanocontainers and nanorattles have been synthesized and characterized that exhibit remarkable control over the release of Ag+ as antimicrobial active species. Their biological...