Université de Fribourg

Simple and fast evaluation of relaxation parameters of magnetic nanoparticles

Lemal, Philipp ; Balog, Sandor ; Ackermann-Hirschi, Liliane ; Taladriz-Blanco, Patricia ; Hirt, Ann M. ; Rothen-Rutishauser, Barbara ; Lattuada, Marco ; Petri-Fink, Alke

In: Journal of Magnetism and Magnetic Materials, 2020, vol. 499, p. 166176

The efficacy of magnetic hyperthermia treatment depends on the optimal available magnetic nanoparticles (MNPs) that are excited in a given alternating magnetic field and viscosity of the region of interest. In this regard, assessing the relevant relaxation parameters is of upmost importance and could improve the speed of development of efficient applications. Here, we demonstrate how to...

Université de Fribourg

Phase transformation of superparamagnetic iron oxide nanoparticles via thermal annealing: implications for hyperthermia applications

Crippa, Federica ; Rodriguez-Lorenzo, Laura ; Hua, Xiao ; Goris, Bart ; Bals, Sara ; Garitaonandia, José S. ; Balog, Sandor ; Burnand, David ; Hirt, Ann M. ; Haeni, Laetitia ; Lattuada, Marco ; Rothen-Rutishauser, Barbara ; Petri-Fink, Alke

In: ACS Applied Nano Materials, 2019, vol. 2, no. 7, p. 4462–4470

Magnetic hyperthermia has the potential to play an important role in cancer therapy and its efficacy relies on the nanomaterials selected. Superparamagnetic iron oxide nanoparticles (SPIONs) are excellent candidates due to the ability of producing enough heat to kill tumor cells by thermal ablation. However, their heating properties depend strongly on crystalline structure and size, which may...

Université de Fribourg

Preparation and characterization of functional silica hybrid magnetic nanoparticles

Digigow, Reinaldo G. ; Dechézelles, Jean-François ; Dietsch, Hervé ; Geissbühler, Isabelle ; Vanhecke, Dimitri ; Geers, Christoph ; Hirt, Ann M. ; Rothen-Rutishauser, Barbara ; Petri-Fink, Alke

In: Journal of Magnetism and Magnetic Materials, 2014, vol. 362, p. 72–79

We report on the synthesis and characterization of functional silica hybrid magnetic nanoparticles (SHMNPs). The co-condensation of 3-aminopropyltriethoxysilane (APTES) and tetraethyl orthosilicate (TEOS) in presence of superparamagnetic iron oxide nanoparticles (SPIONs) leads to hybrid magnetic silica particles that are surface-functionalized with primary amino groups. In this work, a...