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    2 Ergebnisse 1
    Université de Fribourg

    Rauvolfianine, a new antimycobacterial glyceroglycolipid and other constituents from Rauvolfia caffra. Sond (Apocynaceae)

    Messanga, Robert Ebeh ; Ngono Bikobo, Dominique Serge ; Zintchem, Auguste Abouem A. ; Mbabi Nyemeck II, Norbert ; Moni Ndedi, Esther Del Florence ; Betote Diboué, Patrick Hervé ; Nyegue, Maximilienne Ascension ; Atchadé, Alex de Théodore ; Pegnyemb, Dieudonné Emmanuel ; Bochet, Christian G. ; Koert, Ulrich

    In: Natural Product Research, 2018, vol. 32, no. 16, p. 1971-1976

    The chemical investigation of the extract of the dried leaves of Rauvolfia caffra (Sond) (synonym Rauvolfia macrophylla) (Apocynaceae) led to isolation of a new glycoside derivative, rauvolfianine (1) as well as six known compounds: oleanolic acid (2), sitosterol-3-O-β-D-glucopyranoside (3), betulinic acid (4), vellosimine (5), sarpagine (6) and...

    Université de Fribourg

    Antitubercular evaluation of root extract and isolated phytochemicals from Lophira lanceolata against two resistant strains of Mycobacterium tuberculosis

    Nkot, Jeanne Louise ; Ngono Bikobo, Dominique Serge ; Zintchem, Auguste Abouem A. ; Mbabi Nyemeck II, Norbert ; Moni Ndedi, Esther Del Florence ; Betote Diboué, Patrick Hervé ; Pegnyemb, Dieudonné Emmanuel ; Bochet, Christian G. ; Koert, Ulrich

    In: Pharmaceutical Biology, 2018, vol. 56, no. 1, p. 318-324

    Context: The roots of Lophira lanceolata Van Tiegh. Ex Keay (Ochnaceae) have numerous medicinal values in the Central African region. Even though the MeOH extract of the roots has shown antimycobacterial activities, the constituents responsible for this inhibitory activity remain unknown.Objective: Phytochemical investigation of the MeOH root extract of L. lanceolata and determination of the ...

    2 Ergebnisse 1