Université de Neuchâtel

Combining coordination and hydrogen-bonds to form arene ruthenium metalla-assemblies

Appavoo, Divembal ; Carnevale, Diego ; Deschenaux, Robert ; Therrien, Bruno

In: Journal of Organometallic Chemistry, 2016, vol. 824, p. 80-87

Three ureido-pyrimidone derivatives (N-LH) were used to generate in combination with four dinuclear arene ruthenium clips, (p-cymene) 2Ru2(OO boolean AND OO)Cl2 (OO boolean AND OO = oxalato, 2,5-dioxido-1,4-benzoquinonato, 2,5-dichloro-1,4-benzoquinonato, 5,8-dioxido-1,4-naphtoquinonato), twelve cationic arene ruthenium metalla-cycles of the...

Université de Neuchâtel

Exploring new avenues for Arene-Ruthenium complexes : coordination to [60]fullerene, hydrogen bonding assemblies and liquid-crystalline materials

Appavoo-Gupta, Divambal ; Deschenaux, Robert (Dir.)

Thèse de doctorat : Université de Neuchâtel, 2015.

The thesis aims at using arene-ruthenium complexes as building blocks for the synthesis of diverse compounds to obtain potential mesomorphic and/or biological properties. The thesis consists of three main projects. The first project deals with supramolecular assemblies. New supramolecular di- and tetranuclear ruthenium arrangements, the latter bearing a cavity, were designed. H-bonding was...

Université de Neuchâtel

Molecular arene ruthenium cages : new vectors to deliver drugs to cancer cells

Mattsson, Johann ; Therrien, Bruno (Dir.) ; Süss-Fink, Georg (Codir.)

Thèse de doctorat : Université de Neuchâtel, 2010.

Ever since the discovery of cisplatin by Rosenberg in the 1970’s metal complexes as anti-cancer drugs have become an increasing subject of research. Ruthenium as a substitute for the toxic platinum metal has received a lot of attention recently. Organometallic compounds such as arene ruthenium complexes are very versatile and have proven to be active against cancer cells. In order to exploit...