Université de Fribourg

Hepatic mitochondrial energetics during catch-Up fat with high-Fat diets rich in lard or safflower oil

Crescenzo, Raffaella ; Bianco, Francesca ; Falcone, Italia ; Tsalouhidou, Sofia ; Yepuri, Gayathri ; Mougios, Vassilis ; Dulloo, Abdul G. ; Liverini, Giovanna ; Iossa, Susanna

In: Obesity, 2011, p. -

We have investigated whether altered hepatic mitochondrial energetics could explain the differential effects of high-fat diets with low or high ω6 polyunsaturated fatty acid content (lard vs. safflower oil) on the efficiency of body fat recovery (catch-up fat) during refeeding after caloric restriction. After 2 weeks of caloric restriction, rats were isocalorically refed with a low-fat diet (LF)...

Université de Fribourg

Dietary modulation of body composition and insulin sensitivity during catch-up growth in rats: effects of oils rich in n-6 or n-3 PUFA

Yepuri, Gayathri ; Marcelino, Helena ; Shahkhalili, Yasaman ; Aprikian, Olivier ; Macé, Katherine ; Seydoux, Josiane ; Miles-Chan, Jennifer L. ; Montani, Jean-Pierre ; Dulloo, Abdul G.

In: British Journal of Nutrition, 2011, vol. 105, no. 12, p. 1750-1763

The present study investigates whether excessive fat accumulation and hyperinsulinaemia during catch-up growth on high-fat diets are altered by n-6 and n-3 PUFA derived from oils rich in either linoleic acid (LA), α-linolenic acid (ALA), arachidonic acid (AA) or DHA. It has been shown that, compared with food-restricted rats refed a high-fat (lard) diet low in PUFA, those...