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    Université de Fribourg

    Distinct genomic signals of lifespan and life history evolution in response to postponed reproduction and larval diet in Drosophila

    Hoedjes, Katja M. ; van den Heuvel, Joost ; Kapun, Martin ; Keller, Laurent ; Flatt, Thomas ; Zwaan, Bas J.

    In: Evolution Letters, 2019, p. -

    Reproduction and diet are two major factors controlling the physiology of aging and life history, but how they interact to affect the evolution of longevity is unknown. Moreover, although studies of large‐effect mutants suggest an important role of nutrient sensing pathways in regulating aging, the genetic basis of evolutionary changes in lifespan remains poorly understood. To address these...

    Université de Fribourg

    Adaptation to developmental diet influences the response to selection on age at reproduction in the fruit fly

    May, Christina M. ; Heuvel, Joost van den ; Doroszuk, Agnieszka ; Hoedjes, Katja M. ; Flatt, Thomas ; Zwaan, Bas J.

    In: Journal of Evolutionary Biology, 2019, vol. 32, no. 5, p. 425–437

    Experimental evolution (EE) is a powerful tool for addressing how environmental factors influence life‐history evolution. While in nature different selection pressures experienced across the lifespan shape life histories, EE studies typically apply selection pressures one at a time. Here, we assess the consequences of adaptation to three different developmental diets in combination with...