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Université de Fribourg

A multidimensional approach to impulsivity changes in mild Alzheimer’s disease and control participants: cognitive correlates

Rochat, Lucien ; Billieux, Joël ; Juillerat Van der Linden, Anne-Claude ; Annoni, Jean-Marie ; Zekry, Dina ; Gold, Gabriel ; Linden, Martial Van der

In: Cortex, 2013, vol. 49, no. 1, p. 90–100

Introduction: Impulsive behaviors are frequently described in brain-damaged patients, including patients with Alzheimer’s disease (AD). However, few studies have examined impulsivity changes and associated cognitive impairments in AD and healthy controls. Consequently, the first aim of this study was to compare patients with mild AD and matched controls on four dimensions of impulsivity...

Université de Fribourg

Multimodal communication in aphasia: perception and production of co-speech gestures during face-to-face conversation

Preisig, Basil C. ; Eggenberger, Noëmi ; Cazzoli, Dario ; Nyffeler, Thomas ; Gutbrod, Klemens ; Annoni, Jean-Marie ; Meichtry, Jurka R. ; Nef, Tobias ; Müri, René M.

In: Frontiers in Human Neuroscience, 2018, vol. 12, p. -

The role of nonverbal communication in patients with post-stroke language impairment (aphasia) is not yet fully understood. This study investigated how aphasic patients perceive and produce co-speech gestures during face-to-face interaction, and whether distinct brain lesions would predict the frequency of spontaneous co-speech gesturing. For this purpose, we recorded samples of conversations...

Université de Fribourg

Multiple sclerosis decreases explicit counterfactual processing and risk taking in decision making

Simioni, Samanta ; Schluep, Myriam ; Bault, Nadège ; Coricelli, Giorgio ; Kleeberg, Joerg ; Pasquier, Renaud A. Du ; Gschwind, Markus ; Vuilleumier, Patrik ; Annoni, Jean-Marie

In: PLoS ONE, 2012, vol. 7, no. 12, p. e50718

Deficits in decision making (DM) are commonly associated with prefrontal cortical damage, but may occur with multiple sclerosis (MS). There are no data concerning the impact of MS on tasks evaluating DM under explicit risk, where different emotional and cognitive components can be distinguished.Methods: We assessed 72 relapsing-remitting MS (RRMS) patients with mild to moderate disease and 38...

Université de Fribourg

Mutism and amnesia following high-Voltage electrical injury: psychogenic symptomatology triggered by organic dysfunction?

Mishra, Nishant K. ; Russmann, Heike ; Granziera, Cristina ; Maeder, Philippe ; Annoni, Jean-Marie

In: European Neurology, 2011, vol. 66, no. 4, p. 229-234

Background: Mutism and dense retrograde amnesia are found both in organic and dissociative contexts. Moreover, dissociative symptoms may be modulated by right prefrontal activity. A single case, M.R., developed left hemiparesis, mutism and retrograde amnesia after a high-voltage electric shock without evidence of lasting brain lesions. M.R. suddenly recovered from his mutism following a mild...

Université de Fribourg

Neural correlates of maladaptive pain behavior in chronic neck pain - a single case control fMRI study

Beinert, Konstantin ; Mouthon, Audrey ; Keller, Martin ; Mouthon, Michael ; Annoni, Jean-Marie ; Taube, Wolfgang

In: Pain Physician, 2017, vol. 20, no. 1, p. E115–E125

Chronic neck pain patients display functional impairments like decreased range of motion, decreased strength, and reduced sensorimotor function. In patients without structural damage, the reason for the persistence of pain is not well understood. Therefore, it is assumed that in chronic pain states, memory processes play an important role. We have now detected and tested a patient that might...

Université de Fribourg

Neurocognitive aspects of translation

Annoni, Jean-Marie ; Lee-Jahnke, Hannelore ; Sturm, Annegret

In: Meta, 2012, vol. 57, no. 1, p. 96-107

Translation is at the centre of many cognitive domains such as pedagogy, linguistic, pragmatic, neurosciences, and social cognition. This multi-domain aspect is reflected in the current models of translation. Recently, cognitive neurosciences have unraveled some brain mechanisms in the bilingualism domain, and it is quite logical to transfer such knowledge to the field of translation as well as...

Université de Fribourg

Partly segregated cortico-subcortical pathways support phonologic and semantic verbal fluency: A lesion study

Chouiter, Leila ; Holmberg, Josefina ; Manuel, Aurelie L. ; Colombo, Françoise ; Clarke, Stephanie ; Annoni, Jean-Marie ; Spierer, Lucas

In: Neuroscience, 2016, vol. 329, p. 275–283

Verbal fluency refers to the ability to generate as many words as possible in a limited time interval, without repetition and according to either a phonologic (each word begins with a given letter) or a semantic rule (each word belongs to a given semantic category). While current literature suggests the involvement of left fronto-temporal structures in fluency tasks, whether the same or...

Université de Fribourg

Planning of spatially-oriented locomotion following focal brain damage in humans: A pilot study

Hicheur, Halim ; Boujon, Carole ; Wong, Cuebong ; Pham, Quang-Cuong ; Annoni, Jean-Marie ; Bihl, Titus

In: Behavioural Brain Research, 2016, vol. 301, p. 33–42

Motor impairments in human gait following stroke or focal brain damage are well documented. Here, we investigated whether stroke and/or focal brain damage also affect the navigational component of spatially oriented locomotion. Ten healthy adult participants and ten adult brain-damaged patients had to walk towards distant targets from different starting positions (with vision or blindfolded). No...

Université de Fribourg

Posterior SMA Syndrome following subcortical stroke: Contralateral akinesia reversed by visual feedback

Radman, Narges ; Cacioppo, Stephanie ; Spierer, Lucas ; Schmidlin, Eric ; Mayer, Eugène ; Annoni, Jean-Marie

In: Neuropsychologia, 2013, vol. 51, no. 13, p. 2605–2610

Background: The supplementary motor area (SMA) plays a key role in motor programming and production and is involved in internally-cued movements. In neurological populations, SMA syndrome following a lesion to the “SMA proper” is characterized by transient impairment of voluntary movements and motor sequences. This syndrome is assumed to follow on from an interruption of the motor...

Université de Fribourg

Poststroke fatigue following minor infarcts

Radman, Narges ; Staub, Fabienne ; Aboulafia-Brakha, Tatiana ; Berney, Alexandre ; Bogousslavsky, Julien ; Annoni, Jean-Marie

In: Neurology, 2012, p. -

Objective: To explore the potential relationship between fatigue following strokes and poststroke mood, cognitive dysfunction, disability, and infarct site and to determine the predictive factors in the development of poststroke fatigue (PSF) following minor infarcts.Methods: Ninety-nine functionally active patients aged less than 70 years with a first, nondisabling stroke (NIH Stroke Scale score...