Affiner les résultats

Type de document

Collection spécifique

Langue

Domaine

  • Médecine, Technologie, Sciences de l'ingénieur, Informatique désactiver le filtre
Université de Fribourg

Outbreak caused by NDM-1- and RmtB-producing Escherichia coli in Bulgaria

Poirel, Laurent ; Savov, Encho ; Nazli, Arzu ; Trifonova, Angelina ; Todorova, Iva ; Gergova, Ivanka ; Nordmann, Patrice

In: Antimicrobial Agents and Chemotherapy, 2014, vol. 58, no. 4, p. 2472–2474

Twelve consecutive carbapenem-resistant Escherichia coli isolates were recovered from patients (infection or colonization) hospitalized between March and September 2012 in different units at a hospital in Bulgaria. They all produced the carbapenemase NDM-1 and the extended-spectrum-β-lactamase CTX-M-15, together with the 16S rRNA methylase RmtB, conferring high-level resistance to all...

Université de Fribourg

KPC-producing Klebsiella pneumoniae, finally targeting Turkey

Labarca, Jaime ; Poirel, Laurent ; Özdamar, M. ; Turkoglü, S. ; Hakko, E. ; Nordmann, Patrice

In: New Microbes and New Infections, 2014, vol. 2, no. 2, p. 50–51

We report here the first identification of the worldwide spread of Klebsiella pneumoniae carbapenemase-2-producing and carbapenem-resistant K. pneumoniae clone ST258 in Turkey, a country where the distantly-related carbapenemase OXA-48 is known to be endemic. Worryingly, this isolate was also resistant to colistin, now considered to be the last-resort antibiotic for carbapenem-resistant isolates.

Université de Fribourg

Further proofs of concept for the carba NP test

Dortet, Laurent ; Poirel, Laurent ; Nordmann, Patrice

In: Antimicrobial Agents and Chemotherapy, 2014, vol. 58, no. 2, p. 1269–1269

Université de Fribourg

Carbapenemase-producing enterobacteriaceae in Europe: a survey among national experts from 39 countries, february 2013

Glasner, C. ; Albiger, B. ; Buist, G. ; Tambić Andrašević, A. ; Canton, R. ; Carmeli, Y. ; Friedrich, A. W. ; Giske, C. G. ; Glupczynski, Y. ; Gniadkowski, M. ; Livermore, D. M. ; Nordmann, Patrice ; Poirel, Laurent ; Rossolini, G. M. ; Seifert, H. ; Vatopoulos, A. ; Walsh, T. ; Woodford, N. ; Donker, T. ; Monnet, D. L. ; Grundmann, H. ; group, the European Survey on Carbapenemase-Producing Enterobacteriaceae (EuSCAPE) working

In: Euro Surveillance, 2013, vol. 18, no. 28, p. 20525

The spread of carbapenemase-producing Enterobacteriaceae (CPE) is a threat to healthcare delivery, although its extent differs substantially from country to country. In February 2013, national experts from 39 European countries were invited to self-assess the current epidemiological situation of CPE in their country. Information about national management of CPE was also reported. The results...

Université de Fribourg

Evaluation of Etest® strips for detection of KPC and metallo-carbapenemases in Enterobacteriaceae

Girlich, Delphine ; Halimi, Diane ; Zambardi, Gilles ; Nordmann, Patrice

In: Diagnostic Microbiology and Infectious Disease, 2013, vol. 77, no. 3, p. 200–201

The performance of Etest KPC and MBL strips (bioMérieux) was evaluated as compared to other phenotypic tests for detecting carbapenemases of the KPC-type and metallo-β-lactamases, respectively, on 133 well-characterized enterobacterial isolates. KPC and meropenem-containing MP/MPI Etest had high sensitivity (>92 %) and specificity (>97 %).

Université de Fribourg

Strategy for a rapid detection of carbapenemase-producing Enterobacteriaceae

Dortet, Laurent ; Bréchard, Ludivine ; Cuzon, Gaëlle ; Poirel, Laurent ; Nordmann, Patrice

In: Antimicrobial Agents and Chemotherapy, 2014, vol. 58, no. 4, p. 2441-2445

A prospective survey was conducted on 862 Enterobacteriaceae with reduced susceptibility to carbapenems. The Carba NP test, UV spectrophotometry and DNA microarray were used for detecting carbapenemase producers, and results compared to PCR and sequencing. The 172 carbapenemase producers were detected using the Carba NP test and UV spectrophotometry whereas DNA microarray failed to detect IMI...

Université de Fribourg

Comparative evaluation of a novel chromogenic medium (chromID OXA-48) for detection of OXA-48 producing Enterobacteriaceae

Girlich, Delphine ; Anglade, Claire ; Zambardi, Gilles ; Nordmann, Patrice

In: Diagnostic Microbiology and Infectious Disease, 2014, vol. 77, no. 4, p. 296–300

Comparative evaluation of the recently developed chromogenic culture medium chromID OXA-48 (bioMérieux) with chromID CARBA (bioMérieux) and SUPERCARBA showed that chromID OXA-48 and SUPERCARBA media have the highest sensitivity for detection of OXA-48 producing Enterobacteriaceae (91% and 93%) comparatively to chromID CARBA (21 %). The chromID OXA-48 has the highest specificity, with 100%, as...

Université de Fribourg

High rate of faecal carriage of extended-spectrum β-lactamase and OXA-48 carbapenemase-producing Enterobacteriaceae at a University hospital in Morocco

Girlich, D. ; Bouihat, N. ; Poirel, L. ; Benouda, A. ; Nordmann, Patrice

In: Clinical Microbiology and Infection, 2013, p. -

Carbapenemase-producing Enterobacteriaceae isolates are being increasingly reported, particularly from countries surrounding the Mediterranean area. We aimed to quantify the prevalence of carbapenemase- and extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae in rectal swabs from hospitalized patients in a University hospital in Morocco, and to compare the performance of three...