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Human overfeeding experiments: potentials and limitations in obesity research

Schutz, Yves

In: British Journal of Nutrition, 2000, vol. 84, no. 2, p. 135-137

Université de Fribourg

Standing economy: does the heterogeneity in the energy cost of posture maintenance reside in differential patterns of spontaneous weight-shifting?

Miles-Chan, Jennifer L. ; Fares, Elie-Jacques ; Berkachy, Redina ; Jacquet, Philippe ; Isacco, Laurie ; Schutz, Yves ; Montani, Jean-Pierre ; Dulloo, Abdul G.

In: European Journal of Applied Physiology, 2017, vol. 117, no. 4, p. 795–807

Due to sedentarity-associated disease risks, there is much interest in methods to increase low-intensity physical activity. In this context, it is widely assumed that altering posture allocation can modify energy expenditure (EE) to impact body-weight regulation and health. However, we have recently shown the existence of two distinct phenotypes pertaining to the energy cost of...

Université de Fribourg

Reliability of low‐power cycling efficiency in energy expenditure phenotyping of inactive men and women

Fares, Elie-Jacques ; Isacco, Laurie ; Monnard, Cathriona R. ; Miles-Chan, Jennifer L. ; Montani, Jean-Pierre ; Schutz, Yves ; Dulloo, Abdul G.

In: Physiological Reports, 2017, vol. 5, no. 9, p. e13233

Standardized approaches to assess human energy expenditure (EE) are well defined at rest and at moderate to high‐intensity exercise, but not at light intensity physical activities energetically comparable with those of daily life (i.e., 1.5–4 times the resting EE, i.e., 1.5–4 METs). Our aim was to validate a graded exercise test for assessing the energy cost of low‐intensity dynamic...

Université de Fribourg

How dieting makes the lean fatter: from a perspective of body composition autoregulation through adipostats and proteinstats awaiting discovery

Dulloo, Abdul G. ; Jacquet, Jean ; Montani, Jean-Pierre ; Schutz, Yves

In: Obesity Reviews, 2015, vol. 16, p. 25–35

Whether dieting makes people fatter has been a subject of considerable controversy over the past 30 years. More recent analysis of several prospective studies suggest, however, that it is dieting to lose weight in people who are in the healthy normal range of body weight, rather than in those who are overweight or obese, that most strongly and consistently predict future weight gain. This paper...

Université de Fribourg

Dieting and weight cycling as risk factors for cardiometabolic diseases: who is really at risk?

Montani, Jean-Pierre ; Schutz, Yves ; Dulloo, Abdul G.

In: Obesity Reviews, 2015, vol. 16, p. 7–18

Despite the poor prognosis of dieting in obesity management, which often results in repeated attempts at weight loss and hence weight cycling, the prevalence of dieting has increased continuously in the past decades in parallel to the steadily increasing prevalence of obesity. However, dieting and weight cycling are not limited to those who are obese or overweight as substantial proportions of...

Université de Fribourg

Sitting comfortably versus lying down: Is there really a difference in energy expenditure?

Miles-Chan, Jennifer Lynn ; Sarafian, Delphine ; Montani, Jean-Pierre ; Schutz, Yves ; Dulloo, Abdul G.

In: Clinical Nutrition, 2014, vol. 33, no. 1, p. 175–178

Background and aims: Energy expenditure (EE) during sitting is widely assumed to be higher than that while lying down, but supporting evidence is equivocal. Despite this, resting EE in the sitting position is often used as a proxy for basal metabolic rate. Here we investigate whether EE differs in the comfortable seated position compared to supine (lying) position.Methods: EE and respiratory...

Université de Fribourg

Energy gap in the aetiology of body weight gain and obesity: a challenging concept with a complex evaluation and pitfalls

Schutz, Yves ; Byrne, N. M. ; Dulloo, Abdul G. ; Hills, A. P.

In: Obesity Facts, 2014, vol. 7, no. 1, p. 15–25

The concept of energy gap(s) is useful for understanding the consequence of a small daily, weekly, or monthly positive energy balance and the inconspicuous shift in weight gain ultimately leading to overweight and obesity. Energy gap is a dynamic concept: an initial positive energy gap incurred via an increase in energy intake (or a decrease in physical activity) is not constant, may fade out...