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Haute Ecole d'Ingénierie

Schlieren laser Doppler flowmeter for the human optical nerve head with the flicker stimuli

Geiser, Martial ; Truffer, Frederic ; Evequoz, Hugo ; Khayi, Hafid ; Mottet, Benjamin ; Chiquet, Christophe

In: Journal of Biomedical Optics, 2013/18/12/127001/1-127001/5

We describe a device to measure blood perfusion for the human optic nerve head (ONH) based on laser Doppler flowmetry (LDF) with a flicker stimuli of the fovea region. This device is self-aligned for LDF measurements and includes near-infrared pupil observation, green illumination, and observation of the ONH. The optical system of the flowmeter is based on a Schlieren arrangement which collects...

Haute Ecole d'Ingénierie

Compact portable biosensor for arsenic detection in aqueous samples with Escherichia coli bioreporter cells

Truffer, Frederic ; Buffi, Nina ; Merulla, Davide ; Beggah, Siham ; van Lintel, Harald ; Renaud, Philippe ; van der Meer, Jan Roelof ; Geiser, Martial

In: Review of Scientific Instruments, 2014, vol. 85, no. 015120, p. 4

We present a compact portable biosensor to measure arsenic As(III) concentrations in water using Escherichia coli bioreporter cells. Escherichia coli expresses green fluorescent protein in a linearly dependent manner as a function of the arsenic concentration (between 0 and 100μg/L). The device accommodates a small polydimethylsiloxane microfluidic chip that holds the agarose-encapsulated...