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Université de Neuchâtel

Molecular arene ruthenium cages : new vectors to deliver drugs to cancer cells

Mattsson, Johann ; Therrien, Bruno (Dir.) ; Süss-Fink, Georg (Codir.)

Thèse de doctorat : Université de Neuchâtel, 2010.

Ever since the discovery of cisplatin by Rosenberg in the 1970’s metal complexes as anti-cancer drugs have become an increasing subject of research. Ruthenium as a substitute for the toxic platinum metal has received a lot of attention recently. Organometallic compounds such as arene ruthenium complexes are very versatile and have proven to be active against cancer cells. In order to exploit...