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Université de Fribourg

The patent buyout price for Human Papilloma Virus (HPV) vaccine and the ratio of R&D costs to the patent value

Songane, Mario ; Grossmann, Volker

(Working Papers SES ; 510)

Human papillomavirus (HPV) is responsible for almost all of the 530,000 new cases of cervical cancer and approximately 266,000 deaths per year. HPV vaccination is an integral component of the World Health Organization’s global strategy to fight the disease. However, high vaccine prices enforced through patent protection are limiting vaccine expansion, particularly in low- and middle-income...

Université de Fribourg

Patenting government funded innovations as a strategy to increase budget for academic vaccine R&D

Songane, Mario

(Working Papers SES ; 509)

Vaccine development is a lengthy, expensive and risky venture, with the research and development (R&D) process costing billions of dollars. The pre-clinical stage of vaccine R&D is largely performed by academic research institutions, then continued by the pharmaceutical industry though licensing agreements, taking the most promising candidates to the clinical testing stage. Governments play a...

Université de Fribourg

Direct and indirect effects based on changes-in-changes

Huber, Martin ; Schelker, Mark ; Strittmatter, Anthony

(Working Papers SES ; 508)

We propose a novel approach for causal mediation analysis based on changes-in- changes assumptions restricting unobserved heterogeneity over time. This allows disentangling the causal effect of a binary treatment on a continuous outcome into an indirect effect operating through a binary intermediate variable (called mediator) and a direct effect running via other causal mechanisms. We...

Université de Fribourg

A substantial discount on ski passes : a synthetic control analysis

Wallimann, Hannes

(Working Papers SES ; 507)

The synthetic control method serves as an appropriate and promising approach to do quantitative comparison research. However, the method is rarely used in the context of tourism. We fill this research gap by applying the method to the case of a Swiss mountain destination. Alpine tourist destinations have suffered from a declining demand in the last decade. Fewer tourist visit ski resorts....

Université de Fribourg

The effects of gender and parental occupation in the apprenticeship market : an experimental evaluation

Fernandes, Ana ; Huber, Martin ; Plaza, Camila

(Working Papers SES ; 506)

The apprenticeship market is the earliest possible entry into the workforce in developed economies. Since early labor market shocks are likely magnified throughout professional life, avoiding mismatches between talent and occupations e.g. due to gender- or status-based discrimination appears crucial. This experimental study investigates the effects of applicant gender and its interaction with...

Université de Fribourg

Medical and nursery care with endogenous health and longevity

Schünemann, Johannes ; Strulik, Holger ; Trimborn, Timo

(Working Papers SES ; 505)

For the population over 65, nursery care expenditures constitute on average the largest share in total health expenditures. In this paper, we distinguish between medical care, intended to improve ones state of health, and personal care required for daily routine. Personal care can be either carried out autonomously or by a third party. In the course of aging, autonomous personal care is...

Université de Fribourg

An introduction to flexible methods for policy evaluation

Huber, Martin

(Working Papers SES ; 504)

This chapter covers different approaches to policy evaluation for assessing the causal effect of a treatment or intervention on an outcome of interest. As an introduction to causal inference, the discussion starts with the experimental evaluation of a randomized treatment. It then reviews evaluation methods based on selection on observables (assuming a quasi-random treatment given observed...

Université de Fribourg

Health consequences of sterilizations

La Rupelle, Maëlys de ; Dumas, Christelle

(Working Papers SES ; 503)

In India, as in many developing countries, female sterilization is the main contraceptive method: 37% of women older than 25 are sterilized. However, no economic study assesses the effect of sterilization, providing guidance on efficient reproductive health policies. We analyze the consequences of sterilization for maternal health, considering the endogeneity of the decision. We exploit that...

Université de Fribourg

Returns to farm child labor in Tanzania

André, Pierre ; Delesalle, Esther ; Dumas, Christelle

(Working Papers SES ; 502)

In developing countries, the opportunity costs of children’s time can significantly hinder universal education. This paper studies one of these opportunity costs: we estimate the agricultural productivity of children aged 10 to 15 years old using the LSMS-ISA panel survey in Tanzania. Since child labor can be endogenous, we exploit the panel structure of the data and instrument child labor...

Université de Fribourg

What if dividends were tax-exempt? : Evidence from a natural experiment

Isakov, Dušan ; Pérignon, Christophe ; Weisskopf, Jean-Philippe

(Working Papers SES ; 498, revised)

We study the effect of dividend taxes on the payout and investment policy of listed firms and discuss their implications for agency problems. To do so, we exploit a unique setting in Switzerland where some, but not all, firms were suddenly able to pay tax-exempted dividends to their shareholders following the corporate tax reform of 2011. Using a difference-indifferences specification, we...