In: Optics Communications, 2005, vol. 253 (4-6), p. 362-374
Laser spectroscopy of the 2S-Lamb shift in muonic hydrogen (μ−p) is being performed at the Paul Scherrer Institute, Switzerland, to determine the root-mean-square (rms) proton charge radius with 10−3 precision. A multistage laser system has been developed which provides 0.2 mJ pulse energy tunable at 6 μm wavelength. An excimer pumped dye laser is used to drive a...
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In: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2005, vol. 1735(1), p. 79
Homologues of Gpi8p, Gaa1p, Gpi16p, Gpi17p, and Cdc91p are essential components of the GPI transamidase complex that adds glycosylphosphatidylinositols (GPIs 1) to newly synthesized proteins in the ER. In mammalian cells, these five subunits remain stably associated with each other in detergent. In yeast, we find no stable stoichiometric association of Gpi17p with the Gpi8p–Gpi16p–Gaa1p core...
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This article argues for the central role of conversations in knowledge-transformation processes in organizations. Given the importance attributed to conversations in the literature, but also the many conversational routines that often prevent knowledge creation and sharing, an integrative approach for managing knowledge-intensive conversations is needed. The article reviews the academic...
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In: The Journal of Clinical Investigation, 2005, vol. 115(6), p. 1651
Thiazide diuretics enhance renal Na⁺ excretion by blocking the Na⁺-Cl⁻ cotransporter (NCC), and mutations in NCC result in Gitelman syndrome. The mechanisms underlying the accompanying hypocalciuria and hypomagnesemia remain debated. Here, we show that enhanced passive Ca²⁺ transport in the proximal tubule rather than active Ca²⁺ transport in distal convolution explains...
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In: Geomorphology, 2005, vol. 68(3-4), p. 224
For the first time, dendrogeomorphology has been used to investigate spatial and temporal variations of rockfall activity in a protection forest. We report results of 564 cores from 135 severely injured Larix decidua Mill. trees on the west-facing Täschgufer slope, Swiss Alps. While trees sampled reached an age of 297 years on average, the oldest one attained breast height in AD 1318. For...
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In: Cretaceous Research, 2001, vol. 22 (2), p. 173
The Aptian–Lower Turonian hemipelagic sediments of Roter Sattel in the Swiss Prealps are well dated by planktonic foraminifera. Stacking pattern of the limestone-marl alternations and facies evolution allow the identification of sequence boundaries, transgressive surfaces, and maximum-flooding events or condensed sections on at least two hierarchical levels. Calibrated by a precise...
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In: Sedimentary Geology, 2005, vol. 1-4(3), p. 187
This study describes the coeval development of the depositional environments in three areas across the Mut Basin (Southern Turkey) throughout the Late Burdigalian (early Miocene). Antecedent topography and rapid high-amplitude sea-level change are the main controlling factors on stratigraphic architecture and sediment type. Stratigraphic evidence is observed for two high-amplitude (100–150 m)...
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In: Tissue and Cell, 2004, vol. 36 (4), p. 245-248
Previous investigations of the T-system in skeletal muscle fibres described the inter-myofibrillar relationships between T-tubules and the sarcoplasmic reticulum. They disregarded the arrangement of the T-system in the myofibril-free sarcoplasm in the area of muscle fibre nuclei. In the present investigation, the T-system was filled by means of lanthanum incubation and the myofibril-free...
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In: European Journal of Neuroscience, 2004, vol. 20, p. 2664-2670
Oxidative metabolism and cerebral blood flow (CBF) are two of the most important measures in neuroimaging. However, results from concurrent imaging of the two with high spatial and temporal resolution have never been published. We used flavoprotein autofluorescence (AF) and laser speckle imaging (LSI) in the anaesthetized rat to map oxidative metabolism and CBF in response to single vibrissa...
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