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Université de Fribourg

RTerseaanrchs acrtricileptome analysis reveals a major impact of JAK protein tyrosine kinase 2 (Tyk2) on the expression of interferon-responsive and metabolic genes

Vogl, Claus ; Flatt, Thomas ; Fuhrmann, Bernd ; Hofmann, Elisabeth ; Wallner, Barbara ; Stiefvater, Rita ; Kovarik, Pavel ; Strobl, Birgit ; Müller, Mathias

In: BMC Genomics, 2010, vol. 11, no. 199, p. 1-19

Background: Tyrosine kinase 2 (Tyk2), a central component of Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling, has major effects on innate immunity and inflammation. Mice lacking Tyk2 are resistant to endotoxin shock induced by lipopolysaccharide (LPS), and Tyk2 deficient macrophages fail to efficiently induce interferon alpha/beta after LPS treatment. However,...

Consortium of Swiss Academic Libraries

Haemodialysis activates phospholipase A2 enzyme

Vishwanath, B. S. ; Fux, C. A. ; Uehlinger, D. E. ; Frey, B. M. ; Franson, R. C. ; Frey, F. J.

In: Nephrology Dialysis Transplantation, 1996, vol. 11, no. 1, p. 109-116

Consortium of Swiss Academic Libraries

Ageing as a determinant of renal and vascular disease: role of endothelial factors

Barton, Matthias

In: Nephrology Dialysis Transplantation, 2005, vol. 20, no. 3, p. 485-490